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  1. 農学部
  1. 農学部
  2. 学術雑誌掲載論文 (農学部)

Dietary 5-Campestenone (Campest-5-en-3-one) Enhances Fatty Acid Oxidation in Perfused Rat Liver

http://hdl.handle.net/10458/3524
http://hdl.handle.net/10458/3524
5b240673-54a0-4ba9-8048-0c99c2948661
名前 / ファイル ライセンス アクション
fukuda6_J.Nutr.Sci.Vitaminol_vol.52-2_2006.cinii.pdf fukuda6_J.Nutr.Sci.Vitaminol_vol.52-2_2006.cinii.pdf (868.1 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2011-11-29
タイトル
タイトル Dietary 5-Campestenone (Campest-5-en-3-one) Enhances Fatty Acid Oxidation in Perfused Rat Liver
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
キーワード 5-campestenone, perfused rat liver, ketone body production, triacylglycerol (TG) secretion
資源タイプ
資源タイプ journal article
著者 Tamaru, Shizuka

× Tamaru, Shizuka

WEKO 3358

en Tamaru, Shizuka

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Suzuki, Yo

× Suzuki, Yo

WEKO 3359

en Suzuki, Yo

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Sakono, Masanobu

× Sakono, Masanobu

WEKO 3360

en Sakono, Masanobu

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Fukuda, Nobuhiro

× Fukuda, Nobuhiro

WEKO 2814

en Fukuda, Nobuhiro

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Ikeda, Ikuo

× Ikeda, Ikuo

WEKO 3362

en Ikeda, Ikuo

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Konno, Rie

× Konno, Rie

WEKO 3363

en Konno, Rie

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Shimizu, Takeshi

× Shimizu, Takeshi

WEKO 3364

en Shimizu, Takeshi

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Suzuki, Kunio

× Suzuki, Kunio

WEKO 3365

en Suzuki, Kunio

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抄録
内容記述タイプ Abstract
内容記述 The effect of dietary 5-campestenone (campest-5-en-3-one), a chemical modification product of a naturally-occurring plant sterol, campesterol, on lipid metabolism was examined using a rat liver perfusion system. Male Sprague-Dawley rats weighing about 140g were fed a diet supplemented with or without 0.2% 5-campestenone for 14 d. 5-Campestenone feeding resulted in a marked reduction in the concentrations of serum lipids, such as triacylglycerol (TG), cholesterol, phospholipid, and free fatty acid, without influencing food intake or growth. Then, isolated livers from both groups were perfused for 4h in the presence of an exogenous linoelaidic acid substrate. Dietary 5-campestenone markedly elevated hepatic ketone body production, while cumulative secretions of TG, cholesterol, and phospholipid by the livers of rats fed 5-campestenone were all significantly lowered as compared to those fed without the compound; the extent of the reduction was more prominent in the secretion of TG than other lipid components. In addition, the reduction of TG secretion was concomitantly accompanied by the reduced incorporation of both exogenous and endogenous fatty acids into this lipid molecule. These results suggest that dietary 5-campestenone exerts its hypotriglyceridemic effect, at least, in part through an enhanced metabolism of endogenous and exogenous fatty acids to oxidation at the expense of esterification in rat liver.
言語 en
書誌情報 en : Journal of Nutritional Science and Vitaminology

巻 52, 号 2, p. 127-133, 発行日 2006-04
出版者
出版者 The Vitamin Society of Japan
言語 en
出版者
出版者 日本ビタミン学会
言語 ja
ISSN
収録物識別子タイプ ISSN
収録物識別子 03014800
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00703822
PubMed番号
関連タイプ isIdenticalTo
識別子タイプ PMID
関連識別子 16802693
権利
言語 ja
権利情報 日本ビタミン学会
権利
言語 ja
権利情報 本文データは学協会の許諾に基づきCiNiiから複製したものである
他の資源との関係
関連名称 http://ci.nii.ac.jp/naid/110004718471
著者版フラグ
出版タイプ VoR
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Ver.2 2023-07-29 12:44:18.837596
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Cite as

Tamaru, Shizuka, Suzuki, Yo, Sakono, Masanobu, Fukuda, Nobuhiro, Ikeda, Ikuo, Konno, Rie, Shimizu, Takeshi, Suzuki, Kunio, 2006, Dietary 5-Campestenone (Campest-5-en-3-one) Enhances Fatty Acid Oxidation in Perfused Rat Liver: 日本ビタミン学会, 127–133 p.

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