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Clinical manifestations of Henoch–Schönlein purpura nephritis and IgA nephropathy: comparative analysis of data from the Japan Renal Biopsy Registry (J-RBR)
http://hdl.handle.net/10458/00010529
http://hdl.handle.net/10458/000105293a27ed07-c36c-4729-84a6-c4651a2f725e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
本文 (416.0 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2023-02-24 | |||||
| タイトル | ||||||
| タイトル | Clinical manifestations of Henoch–Schönlein purpura nephritis and IgA nephropathy: comparative analysis of data from the Japan Renal Biopsy Registry (J-RBR) | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | Henӧch-Schӧnlein purpura nephritis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | IgA nephropathy | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | renal biopsy | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | registry | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | glomerulonephritis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | age distribution | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
小松, 弘幸
× 小松, 弘幸× 藤元, 昭一× Yoshikawa, Norishige× Kitamura, Hiroshi× Sugiyama, Hitoshi× Yokoyama, Hitoshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background The clinical presentation of Henoch–Schönlein purpura nephritis （HSPN） has not been thoroughly investigated among patients of different ages. We therefore compared the features of HSPN and IgA nephropathy （IgAN） based on data from the Japan Renal Biopsy Registry （J-RBR）. Methods This cross-sectional study analyzed data from patients who were registered in the J-RBR between 2007 and 2012. Clinico-pathological findings at diagnosis were compared among children （aged ≤18 years）, adult （aged 19–64 years） and elderly （aged ≥65 years） patients with HSPN （n = 513） and IgAN （n = 5679）. Results The age at diagnosis considerably differed between HSPN and IgAN; HSPN peaked at 1–19 and at 60–69 years, whereas IgAN peaked at 30–39 years. The clinical features were significantly more severe for HSPN than IgAN, especially proteinuria （children, 1.28 vs. 0.57; adult, 1.95 vs. 1.05; elderly patients, 2.71 vs. 1.64 g/day）, and low albumin levels （children, 3.72 vs. 4.13; adults, 3.62 vs. 3.99; elderly patients, 3.07 vs. 3.57 g/dL）. The rate （%） of histologically classified endocapillary proliferative or crescentic glomerulonephritis was higher in patients with HSPN than with IgAN. Multiple regression analysis revealed that low albumin level and high BP were independent factors associated with decreased estimated glomerular filtration rates in adult and elderly patients with HSPN. Conclusions Age at HSPN diagnosis was bimodally distributed, and the clinical features of HSPN were more severe than those of IgAN across all age groups. |
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| 書誌情報 |
en : Clinical and Experimental Nephrology 巻 20, 号 4, p. 552-560, 発行日 2016 |
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| 出版者 | ||||||
| 出版者 | Springer | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13421751 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 26456327 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1007/s10157-015-1177-0 | |||||
| 権利 | ||||||
| 権利情報 | (C) The Author(s) 2015. This article is published with open access at Springerlink.com | |||||
| 関連サイト | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1007/s10157-015-1177-0 | |||||
| 関連名称 | Publisher's web site | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
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Komatsu, Hiroyuki, Fujimoto, Shouichi, Yoshikawa, Norishige, Kitamura, Hiroshi, Sugiyama, Hitoshi, Yokoyama, Hitoshi, 2016, Clinical manifestations of Henoch–Schönlein purpura nephritis and IgA nephropathy: comparative analysis of data from the Japan Renal Biopsy Registry (J-RBR): Springer, 552–560 p.
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