WEKO3
アイテム
Relationship of immunonutritional factor with changes in liver volume after portal vein embolization
http://hdl.handle.net/10458/00010381
http://hdl.handle.net/10458/00010381fd7f1f2b-7d21-429f-8df5-7ccc2ea872b1
| 名前 / ファイル | ライセンス | アクション |
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1-s2.0-S2589845022000367-main (383.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||||||||||
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| 公開日 | 2022-06-23 | |||||||||||||||||||||||||||||
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| タイトル | Relationship of immunonutritional factor with changes in liver volume after portal vein embolization | |||||||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||||||||||
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| 資源タイプ | journal article | |||||||||||||||||||||||||||||
| 著者 |
七島, 篤志
× 七島, 篤志
WEKO
33886
× 旭吉, 雅秀× 今村, 直哉
WEKO
19941
× 濱田, 剛臣× 甲斐, 健吾
WEKO
33883
× Tanoue, Yukinori× Yano, Koichi× 濱田, 剛臣× Kitamura, Eiji× 鈴木, 康人
WEKO
33632
× Tahira, Kousei× 河野, 文耶× Nagayasu, Takeshi |
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| 抄録 | ||||||||||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||||||||||
| 内容記述 | Background To identify predictors of changes in hepatic volumes after portal vein embolization, we examined the relationship with preoperative nutritional and immunological parameters. Patients and Methods Ninety-three patients who underwent portal vein embolization were included. The control group comprised 13 patients who underwent right hepatectomy without portal vein embolization. Computed tomographic volumetric parameter was measured for changes in embolized and nonembolized liver. Correlation with various candidates of immunonutritional parameters was examined. Results Difference in increased liver ratio was 9.1%. C-reactive protein levels significantly increased after portal vein embolization （P < .01）, whereas albumin and total cholesterol levels significantly decreased, respectively （P < .01）. The C-reactive protein/albumin ratio, prognostic nutritional index, Controlling Nutritional Status score, and modified Glasgow Prognostic Score were significantly different, respectively （P < .01）. Prothrombin activity and total cholesterol level significantly correlated with the increased change in nonembolized liver （P < .05）. The C-reactive protein and C-reactive protein/albumin ratio after portal vein embolization negatively correlated with hypertrophic ratio （P < .05）. By comparing posthepatectomy outcomes between 64 patients undergoing portal vein embolization and 13 who did not, the prevalence of severe complications and mortality in the portal vein embolization group was not different from that in the non–portal vein embolization group. Liver activity at 15 minutes > 0.92 and increased liver volume ≥ 10% tended to correlate with lower prevalence of severe complications. Only increased intraoperative blood loss ≥ 1,500 mL was significantly associated with morbidity and mortality （P < .05）. Conclusion Contrary to our hypothesis, immunonutritional parameters, except C-reactive protein and C-reactive protein/albumin ratio, did not reflect hypertrophy after portal vein embolization. Although it is difficult to predict the hypertrophic degree, the strategy of scheduled hepatectomy should be switched in case of impaired inflammatory status after portal vein embolization. |
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| 書誌情報 |
en : Surgery Open Science 巻 9, p. 117-124, 発行日 2022-07 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||||||||
| 収録物識別子 | 25898450 | |||||||||||||||||||||||||||||
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| 関連タイプ | isIdenticalTo | |||||||||||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.1016/j.sopen.2022.05.012 | |||||||||||||||||||||||||||||
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| 権利情報 | © 2022 The Author(s). Published by Elsevier Inc. | |||||||||||||||||||||||||||||
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| 内容記述タイプ | Other | |||||||||||||||||||||||||||||
| 内容記述 | application/pdf | |||||||||||||||||||||||||||||
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| 出版タイプ | VoR | |||||||||||||||||||||||||||||
