Fundamental and distinct ways for irreversible creation of chromatin structure plasticity of proximal 5'-upstream regions of Pax5, Aiolos, EBF1 and OBF1 genes with epigenetic modifications for gain of new cell function to exclude accumulated IgM H- and L-chains in individual clones of HDAC2(-/-) DT40 mutants through various generations during continuous cultivation

fig5

WEKO3

lat lon distance

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