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Reciprocal Effects of Dietary Sesamin on Ketogenesis and Triacylglycerol Secretion by the Rat Liver
http://hdl.handle.net/10458/3532
http://hdl.handle.net/10458/3532a2372ffa-eb11-46a7-af1c-ebf2fe4d99a5
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
FN_865.pdf (986.1 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2011-12-02 | |||||
| タイトル | ||||||
| タイトル | Reciprocal Effects of Dietary Sesamin on Ketogenesis and Triacylglycerol Secretion by the Rat Liver | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | Sesamin, Triacylglycerol secretion, Ketone body production, Perfused rat liver, Hypotriglyceridemic effect | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Fukuda, Nobuhiro
× Fukuda, Nobuhiro× Miyagi, Chika× Zhang, Lei× Jayasooriya, Anura P.× 窄野, 昌信× Yamamoto, Kyosuke× Ide, Takashi× 菅野, 道廣 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The effects of dietary sesamin （a mixture of sesamin and episesamin, 1:1, w/w） on ketone body production and lipid secretion were studied in isolated perfused liver from rats given sesamin. Feeding sesamin at the dietary level of 0.2% from 14 to 16 d resulted in an enlargement of liver weight. Ketone body production was significantly elevated in the livers perfused with oleic acid in comparison with those perfused without an exogenous-free fatty acid, and sesamin feeding caused a stimulation of ketone body production, especially when exogenous oleic acid was provided. On the other hand, the ratio of beta-hydroxybutyrate to acetoacetate, an index of mitochondrial redox potential, tended to increase in the livers perfused with oleic acid compared with those without fatty acid, thought it was consistently lowered by dietary sesamin. The cumulative secretion of triacylglycerol, but not of cholesterol, by the livers from sesamin-fed rats was decreased markedly, especially when exogenous oleic acid was provided, suggesting an inverse relationship between the rates of ketogenesis and triacylglycerol secretion. These results suggest that dietary sesamin exerts its hypotriglyceridemic effect at least in part through an enhanced metabolism of exogenous-free fatty acid to oxidation at the expense of esterification in rat liver. | |||||
| 言語 | en | |||||
| 書誌情報 |
en : Journal of Nutritional Science and Vitaminology 巻 44, 号 5, p. 715-722, 発行日 1998-10 |
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| 出版者 | ||||||
| 出版者 | The Vitamin Society of Japan | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | 日本ビタミン学会 | |||||
| 言語 | ja | |||||
| 出版者 | ||||||
| 出版者 | University of Tokyo Press | |||||
| 言語 | en | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 03014800 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00703822 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 9919491 | |||||
| 権利 | ||||||
| 言語 | ja | |||||
| 権利情報 | 日本ビタミン学会 | |||||
| 権利 | ||||||
| 言語 | ja | |||||
| 権利情報 | 本文データは学協会の許諾に基づきJournal@rchiveから複製したものである | |||||
| 他の資源との関係 | ||||||
| 関連名称 | http://dx.doi.org/10.3177/jnsv.44.715 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
