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Reactivation of hepatitis C virus caused by steroid monotherapy for sudden deafness
http://hdl.handle.net/10458/0002000871
http://hdl.handle.net/10458/00020008712a94de21-29be-4da6-ab16-61c4e2bcbe2c
| 名前 / ファイル | ライセンス | アクション |
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本文 (835 KB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2024-12-24 | |||||||
| タイトル | ||||||||
| タイトル | Reactivation of hepatitis C virus caused by steroid monotherapy for sudden deafness | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| キーワード | HCV reactivation | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| キーワード | Steroid | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| キーワード | Sudden deafness | |||||||
| 資源タイプ | ||||||||
| 資源タイプ | journal article | |||||||
| アクセス権 | ||||||||
| 著者 |
金子, 博樹
× 金子, 博樹× 大園, 芳範× 岩切, 久芳× 畑田, 紘志× 内山, 尚美× Komaki, Yuri
× 中村, 憲一× 蓮池, 悟× 永田, 賢治× 河上, 洋 |
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| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Hepatitis C virus (HCV) reactivation has been reported to be caused due to several anticancer drugs and immunosuppressive agents; however, HCV reactivation after steroid monotherapy has rarely been reported. Here, we report the case of a 65-year-old Japanese man with HCV infection who developed HCV reactivation after the administration of prednisolone (PSL) for 6 days for sudden deafness. In the patient history, the positivity for anti-HCV antibody was observed, but serum level of HCV RNA was not measured. Two months after PSL administration, the patient experienced an alanine aminotransferase (ALT) flare and the serum level of HCV RNA was observed to be 6.2 log IU/mL; then, the patient was admitted to our hospital for hepatitis treatment. Based on the clinical course and laboratory findings, the patient was diagnosed with HCV reactivation. Although the ALT levels decreased spontaneously during follow-up, they did not drop to normal range; subsequently, sofosbuvir and ledipasvir treatments were started. A sustained virological response 24 weeks after the end of treatment was achieved. This case study suggests that HCV reactivation with hepatitis flare can occur even after a steroid monotherapy, and doctors should pay attention to HCV reactivation when administering PSL for patients with HCV infection. | |||||||
| 言語 | en | |||||||
| 内容記述 | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Citation: Kaneko, H., Ozono, Y., Iwakiri, H. et al. Reactivation of hepatitis C virus caused by steroid monotherapy for sudden deafness. Clin J Gastroenterol 17, 505–510 (2024). https://doi.org/10.1007/s12328-024-01944-9 |
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| 言語 | en | |||||||
| bibliographic_information |
en : Clinical Journal of Gastroenterology 巻 17, 号 3, p. 505-510, 発行日 2024-04-08 |
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| 出版者 | ||||||||
| 出版者 | Springer Science and Business Media LLC | |||||||
| 言語 | en | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 1865-7257 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | EISSN | |||||||
| 収録物識別子 | 1865-7265 | |||||||
| item_10001_relation_14 | ||||||||
| 関連タイプ | isVersionOf | |||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | https://doi.org/10.1007/s12328-024-01944-9 | |||||||
| 権利 | ||||||||
| 言語 | en | |||||||
| 権利情報 | © The Author(s) 2024 | |||||||
| 出版タイプ | ||||||||
| 出版タイプ | VoR | |||||||
