| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-12-24 |
| タイトル |
|
|
タイトル |
Prevalence of chromosome 8p11.2 translocations and correlation with myeloid and lymphoid neoplasms associated with FGFR1 abnormalities in a consecutive cohort from nine institutions in Japan |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
8p11 |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Eosinophilia |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
FGFR1 |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
Usuki, Kensuke
亀田, 拓郎
Kawano, Noriaki
Ito, Tomoki
Hashimoto, Yoshinori
幣, 光太郎
Kawano, Hiroshi
関根, 雅明
Toyama, Takanori
Iizuka, Hiromitsu
Sato, Seiichi
Takeuchi, Masanori
Ishizaki, Junzo
Maeda, Kouichi
中井, 陸運
Yamashita, Kiyoshi
久冨木, 庸子
下田, 和哉
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| 抄録 |
|
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内容記述タイプ |
Abstract |
|
内容記述 |
Myeloid and lymphoid neoplasms associated with FGFR1 abnormalities (MLN-FGFR1 abnormalities) are rare hematologic malignancies associated with chromosome 8p11.2 abnormalities. Translocations of 8p11.2 were detected in 10 of 17,039 (0.06%) unique patient cytogenetic studies performed at nine institutions in Japan. No inversions or insertions of 8p11.2 were detected. Among the 10 patients with 8p11.2 translocations, three patients were diagnosed with MLN-FGFR1 abnormalities, which were confirmed by FISH analysis. Peripheral blood eosinophilia was observed in all three patients, and all progressed to AML or T-lymphoblastic lymphoma/leukemia. The prevalence of 8p11.2 translocations in clinical practice and the proportion of MLN-FGFR1 abnormalities in patients with 8p11.2 translocations in Japan were consistent with those in previous reports from Western countries. |
|
言語 |
en |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Citation:
Usuki, K., Kameda, T., Kawano, N. et al. Prevalence of chromosome 8p11.2 translocations and correlation with myeloid and lymphoid neoplasms associated with FGFR1 abnormalities in a consecutive cohort from nine institutions in Japan. Int J Hematol 119, 722–727 (2024). https://doi.org/10.1007/s12185-024-03740-0 |
|
言語 |
en |
| 書誌情報 |
en : International Journal of Hematology
巻 119,
号 6,
p. 722-727,
発行日 2024-03-08
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| 出版者 |
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出版者 |
Springer Science and Business Media LLC |
|
言語 |
en |
| ISSN |
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|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0925-5710 |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
1865-3774 |
| DOI |
|
|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1007/s12185-024-03740-0 |
| 権利 |
|
|
言語 |
en |
|
権利情報Resource |
© The Author(s) 2024 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
本文 (665 KB)
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