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Amniocentesis for threatened preterm labor with intact membranes and the impact on adverse outcome in infants born at 22 to 28 weeks of gestation
http://hdl.handle.net/10458/0002000459
http://hdl.handle.net/10458/00020004596a1620df-7ca5-4e30-84a4-7c0e53e02ad9
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2024-01-26 | |||||
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| タイトル | Amniocentesis for threatened preterm labor with intact membranes and the impact on adverse outcome in infants born at 22 to 28 weeks of gestation | |||||
| 言語 | en | |||||
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| 言語 | eng | |||||
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| 資源タイプ | journal article | |||||
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| 著者 |
牧, 洋平
× 牧, 洋平× 古川, 誠志× 児玉, 由紀× 鮫島, 浩× 池ノ上, 克 |
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| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background It remains unclear whether performing amniocentesis to detect intra-amniotic infection is useful for improving neonatal outcomes. Aims To determine the efficacy of amniocentesis on the neonatal outcomes in women exhibiting threatened preterm labor and intact membranes. Study design Retrospective cohort study Subjects A total of 174 women with threatened preterm labor and intact membranes at 22 to 33 weeks of gestation. Women with obvious clinical chorioamnionitis, multifetal pregnancy and/or major anomalies were excluded. Outcome Measures Neonatal short- and long-term outcomes Results Sixty-seven women underwent amniocentesis (Tap group), while the remaining 107 did not. The prevalence of a positive Gram stain or a positive culture result was 10% in the Tap group. The overall outcomes were not statistically different between the two groups, with the exception of borderline significance (p = 0.052) in long-term outcomes, favoring the Tap group. We performed a subgroup analysis focusing on infants born at 22–28 weeks of gestation. Consequently, the Tap group had better neonatal outcomes than the no-Tap group with respect to both short-term (OR 0.19, 95%CI 0.07–0.55) and long-term (OR 0.15, 0.05–0.46) outcomes. A multivariate analysis revealed that after adjusting confounding factors, the gestational age at delivery (OR 0.4, 0.3–0.7) and amniocentesis (OR 0.1, 0.02–0.3) remained significantly different. Conclusions Amniocentesis is useful for improving neonatal outcomes in infants born at 22–28 weeks of gestation to women exhibiting preterm labor and intact membranes. |
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| 言語 | en | |||||
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| 内容記述タイプ | Other | |||||
| 内容記述 | Citation: Maki Y, Furukawa S, Kodama Y, Sameshima H, Ikenoue T. Amniocentesis for threatened preterm labor with intact membranes and the impact on adverse outcome in infants born at 22 to 28 weeks of gestation. Early Hum Dev. 2015 May;91(5):333-7. doi: 10.1016/j.earlhumdev.2015.03.006. Epub 2015 Apr 10. PMID: 25866900. |
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| 言語 | en | |||||
| 書誌情報 |
en : Early Human Development 巻 91, 号 5, p. 333-337, 発行日 2015-05 |
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| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| 言語 | en | |||||
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| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 03783782 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1016/j.earlhumdev.2015.03.006 | |||||
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| 出版タイプ | NA | |||||
