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  1. 医学獣医学総合研究科
  1. 医学獣医学総合研究科
  2. 医学獣医学総合研究科学術雑誌掲載論文

Amniocentesis for threatened preterm labor with intact membranes and the impact on adverse outcome in infants born at 22 to 28 weeks of gestation

http://hdl.handle.net/10458/0002000459
http://hdl.handle.net/10458/0002000459
6a1620df-7ca5-4e30-84a4-7c0e53e02ad9
Item type 学術雑誌論文 / Journal Article(1)
公開日 2024-01-26
タイトル
タイトル Amniocentesis for threatened preterm labor with intact membranes and the impact on adverse outcome in infants born at 22 to 28 weeks of gestation
言語 en
言語
言語 eng
資源タイプ
資源タイプ journal article
アクセス権
著者 牧, 洋平

× 牧, 洋平

WEKO 28623

ja 牧, 洋平

ja-Kana マキ, ヨウヘイ

en Maki, Yohei


Search repository
古川, 誠志

× 古川, 誠志

WEKO 7807

en Furukawa, Seishi

ja 古川, 誠志

ja-Kana フルカワ, セイシ


Search repository
児玉, 由紀

× 児玉, 由紀

WEKO 24698
e-Rad_Researcher 30305081

ja 児玉, 由紀

ja-Kana コダマ, ユキ

en Kodama, Yuki


Search repository
鮫島, 浩

× 鮫島, 浩

WEKO 7804
e-Rad_Researcher 50274775

ja 鮫島, 浩

ja-Kana サメシマ, ヒロシ

en Sameshima, Hiroshi


Search repository
池ノ上, 克

× 池ノ上, 克

WEKO 7806

en Ikenoue, Tsuyomu

ja 池ノ上, 克

ja-Kana イケノウエ, ツヨム


Search repository
抄録
内容記述タイプ Abstract
内容記述 Background
It remains unclear whether performing amniocentesis to detect intra-amniotic infection is useful for improving neonatal outcomes.

Aims
To determine the efficacy of amniocentesis on the neonatal outcomes in women exhibiting threatened preterm labor and intact membranes.

Study design
Retrospective cohort study

Subjects
A total of 174 women with threatened preterm labor and intact membranes at 22 to 33 weeks of gestation. Women with obvious clinical chorioamnionitis, multifetal pregnancy and/or major anomalies were excluded.

Outcome Measures
Neonatal short- and long-term outcomes

Results
Sixty-seven women underwent amniocentesis (Tap group), while the remaining 107 did not. The prevalence of a positive Gram stain or a positive culture result was 10% in the Tap group. The overall outcomes were not statistically different between the two groups, with the exception of borderline significance (p = 0.052) in long-term outcomes, favoring the Tap group. We performed a subgroup analysis focusing on infants born at 22–28 weeks of gestation. Consequently, the Tap group had better neonatal outcomes than the no-Tap group with respect to both short-term (OR 0.19, 95%CI 0.07–0.55) and long-term (OR 0.15, 0.05–0.46) outcomes. A multivariate analysis revealed that after adjusting confounding factors, the gestational age at delivery (OR 0.4, 0.3–0.7) and amniocentesis (OR 0.1, 0.02–0.3) remained significantly different.

Conclusions
Amniocentesis is useful for improving neonatal outcomes in infants born at 22–28 weeks of gestation to women exhibiting preterm labor and intact membranes.
言語 en
内容記述
内容記述タイプ Other
内容記述 Citation:
Maki Y, Furukawa S, Kodama Y, Sameshima H, Ikenoue T. Amniocentesis for threatened preterm labor with intact membranes and the impact on adverse outcome in infants born at 22 to 28 weeks of gestation. Early Hum Dev. 2015 May;91(5):333-7. doi: 10.1016/j.earlhumdev.2015.03.006. Epub 2015 Apr 10. PMID: 25866900.
言語 en
書誌情報 en : Early Human Development

巻 91, 号 5, p. 333-337, 発行日 2015-05
出版者
出版者 Elsevier
言語 en
ISSN
収録物識別子タイプ ISSN
収録物識別子 03783782
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.earlhumdev.2015.03.006
著者版フラグ
出版タイプ NA
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Cite as

牧, 洋平, 古川, 誠志, 児玉, 由紀, 鮫島, 浩, 池ノ上, 克, 2015, Amniocentesis for threatened preterm labor with intact membranes and the impact on adverse outcome in infants born at 22 to 28 weeks of gestation: Elsevier, 333–337 p.

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