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  1. 医学獣医学総合研究科
  1. 医学獣医学総合研究科
  2. 医学獣医学総合研究科学術雑誌掲載論文

Extremely Low Genomic Diversity of Rickettsia japonica Distributed in Japan

http://hdl.handle.net/10458/0002000410
http://hdl.handle.net/10458/0002000410
9c8c5e45-eefd-44bd-a082-9c3edf36bd00
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arzuba2017.pdf article (465 KB)
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Item type 学術雑誌論文 / Journal Article(1)
公開日 2023-12-22
タイトル
タイトル Extremely Low Genomic Diversity of Rickettsia japonica Distributed in Japan
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
キーワード rickettsia
キーワード
言語 en
主題Scheme Other
キーワード intracellular bacteria
キーワード
言語 en
主題Scheme Other
キーワード intra-species genomic diversity
キーワード
言語 en
主題Scheme Other
キーワード genome evolution
キーワード
言語 en
主題Scheme Other
キーワード generation time
資源タイプ
資源タイプ journal article
著者 Arzuba, Akter

× Arzuba, Akter

WEKO 27825

en Arzuba, Akter


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Ooka, Tadasuke

× Ooka, Tadasuke

WEKO 27808

en Ooka, Tadasuke


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Gotoh, Yasuhiro

× Gotoh, Yasuhiro

WEKO 27809

en Gotoh, Yasuhiro


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Yamamoto, Seigo

× Yamamoto, Seigo

WEKO 27828

en Yamamoto, Seigo


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Fujita, Hiromi

× Fujita, Hiromi

WEKO 27829

en Fujita, Hiromi


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Terasoma, Fumio

× Terasoma, Fumio

WEKO 27830

en Terasoma, Fumio


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Kida, Kouji

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en Kida, Kouji

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Taira, Masakatsu

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en Taira, Masakatsu

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Nakadouzono, Fumiko

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en Nakadouzono, Fumiko

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Gokuden, Mutsuyo

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en Gokuden, Mutsuyo

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Hirano, Manabu

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en Hirano, Manabu

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Miyashiro, Mamoru

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en Miyashiro, Mamoru

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Inari, Kouichi

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Shimazu, Yukie

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Tabara, Kenji

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Toyoda, Atsushi

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en Toyoda, Atsushi

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Yoshimura, Dai

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Itoh, Takehiko

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Kitano, Tomokazu

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Sato, Mitsuhiko P.

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Katsura, Keisuke

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en Katsura, Keisuke


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Mondal, Shakhinur Islam

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Ogura, Yoshitoshi

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Ando, Shuji

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Hayashi, Tetsuya

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抄録
内容記述タイプ Abstract
内容記述 Rickettsiae are obligate intracellular bacteria that have small genomes as a result of reductive evolution. Many Rickettsia species of the spotted fever group (SFG) cause tick-borne diseases known as “spotted fevers”. The life cycle of SFG rickettsiae is closely associated with that of the tick, which is generally thought to act as a bacterial vector and reservoir that maintains the bacterium through transstadial and transovarial transmission. Each SFG member is thought to have adapted to a specific tick species, thus restricting the bacterial distribution to a relatively limited geographic region. These unique features of SFG rickettsiae allow investigation of how the genomes of such biologically and ecologically specialized bacteria evolve after genome reduction and the types of population structures that are generated. Here, we performed a nationwide, high-resolution phylogenetic analysis of Rickettsia japonica, an etiological agent of Japanese spotted fever that is distributed in Japan and Korea. The comparison of complete or nearly complete sequences obtained from 31 R. japonica strains isolated from various sources in Japan over the past 30 years demonstrated an extremely low level of genomic diversity. In particular, only 34 single nucleotide polymorphisms were identified among the 27 strains of the major lineage containing all clinical isolates and tick isolates from the three tick species. Our data provide novel insights into the biology and genome evolution of R. japonica, including the possibilities of recent clonal expansion and a long generation time in nature due to the long dormant phase associated with tick life cycles.
言語 en
内容記述
内容記述タイプ Other
内容記述 Citation:
Akter A, Ooka T, Gotoh Y, Yamamoto S, Fujita H, Terasoma F, Kida K, Taira M, Nakadouzono F, Gokuden M, Hirano M, Miyashiro M, Inari K, Shimazu Y, Tabara K, Toyoda A, Yoshimura D, Itoh T, Kitano T, Sato MP, Katsura K, Mondal SI, Ogura Y, Ando S, Hayashi T. Extremely Low Genomic Diversity of Rickettsia japonica Distributed in Japan. Genome Biol Evol. 2017 Jan 1;9(1):124-133. doi: 10.1093/gbe/evw304. PMID: 28057731; PMCID: PMC5381555.
言語 en
書誌情報 en : Genome Biology and Evolution

巻 9, 号 1, p. 124-133
出版者
出版者 Oxford
言語 en
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1093/gbe/evw304
権利
言語 en
権利情報 © The Author(s) 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.
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出版タイプ VoR
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Cite as

Arzuba, Akter, Ooka, Tadasuke, Gotoh, Yasuhiro, Yamamoto, Seigo, Fujita, Hiromi, Terasoma, Fumio, Kida, Kouji, Taira, Masakatsu, Nakadouzono, Fumiko, Gokuden, Mutsuyo, Hirano, Manabu, Miyashiro, Mamoru, Inari, Kouichi, Shimazu, Yukie, Tabara, Kenji, Toyoda, Atsushi, Yoshimura, Dai, Itoh, Takehiko, Kitano, Tomokazu, Sato, Mitsuhiko P., Katsura, Keisuke, Mondal, Shakhinur Islam, Ogura, Yoshitoshi, Ando, Shuji, Hayashi, Tetsuya, n.d., Extremely Low Genomic Diversity of Rickettsia japonica Distributed in Japan: Oxford, 124–133 p.

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