| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2023-12-22 |
| タイトル |
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|
タイトル |
Extremely Low Genomic Diversity of Rickettsia japonica Distributed in Japan |
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言語 |
en |
| 言語 |
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|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
キーワード |
rickettsia |
| キーワード |
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|
言語 |
en |
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主題Scheme |
Other |
|
キーワード |
intracellular bacteria |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
キーワード |
intra-species genomic diversity |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
キーワード |
genome evolution |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
|
キーワード |
generation time |
| 資源タイプ |
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資源タイプ |
journal article |
| 著者 |
Arzuba, Akter
Ooka, Tadasuke
Gotoh, Yasuhiro
Yamamoto, Seigo
Fujita, Hiromi
Terasoma, Fumio
Kida, Kouji
Taira, Masakatsu
Nakadouzono, Fumiko
Gokuden, Mutsuyo
Hirano, Manabu
Miyashiro, Mamoru
Inari, Kouichi
Shimazu, Yukie
Tabara, Kenji
Toyoda, Atsushi
Yoshimura, Dai
Itoh, Takehiko
Kitano, Tomokazu
Sato, Mitsuhiko P.
Katsura, Keisuke
Mondal, Shakhinur Islam
Ogura, Yoshitoshi
Ando, Shuji
Hayashi, Tetsuya
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Rickettsiae are obligate intracellular bacteria that have small genomes as a result of reductive evolution. Many Rickettsia species of the spotted fever group (SFG) cause tick-borne diseases known as “spotted fevers”. The life cycle of SFG rickettsiae is closely associated with that of the tick, which is generally thought to act as a bacterial vector and reservoir that maintains the bacterium through transstadial and transovarial transmission. Each SFG member is thought to have adapted to a specific tick species, thus restricting the bacterial distribution to a relatively limited geographic region. These unique features of SFG rickettsiae allow investigation of how the genomes of such biologically and ecologically specialized bacteria evolve after genome reduction and the types of population structures that are generated. Here, we performed a nationwide, high-resolution phylogenetic analysis of Rickettsia japonica, an etiological agent of Japanese spotted fever that is distributed in Japan and Korea. The comparison of complete or nearly complete sequences obtained from 31 R. japonica strains isolated from various sources in Japan over the past 30 years demonstrated an extremely low level of genomic diversity. In particular, only 34 single nucleotide polymorphisms were identified among the 27 strains of the major lineage containing all clinical isolates and tick isolates from the three tick species. Our data provide novel insights into the biology and genome evolution of R. japonica, including the possibilities of recent clonal expansion and a long generation time in nature due to the long dormant phase associated with tick life cycles. |
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言語 |
en |
| 内容記述 |
|
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内容記述タイプ |
Other |
|
内容記述 |
Citation:
Akter A, Ooka T, Gotoh Y, Yamamoto S, Fujita H, Terasoma F, Kida K, Taira M, Nakadouzono F, Gokuden M, Hirano M, Miyashiro M, Inari K, Shimazu Y, Tabara K, Toyoda A, Yoshimura D, Itoh T, Kitano T, Sato MP, Katsura K, Mondal SI, Ogura Y, Ando S, Hayashi T. Extremely Low Genomic Diversity of Rickettsia japonica Distributed in Japan. Genome Biol Evol. 2017 Jan 1;9(1):124-133. doi: 10.1093/gbe/evw304. PMID: 28057731; PMCID: PMC5381555. |
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言語 |
en |
| 書誌情報 |
en : Genome Biology and Evolution
巻 9,
号 1,
p. 124-133
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| 出版者 |
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出版者 |
Oxford |
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言語 |
en |
| DOI |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1093/gbe/evw304 |
| 権利 |
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|
言語 |
en |
|
権利情報 |
© The Author(s) 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. |
| 著者版フラグ |
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出版タイプ |
VoR |
article (465 KB)
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