| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2023-12-11 |
| タイトル |
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タイトル |
Effects of branched-chain amino acids on immune status of young racing horses |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| キーワード |
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|
言語 |
en |
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主題Scheme |
Other |
|
キーワード |
branched-chain amino acid |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
|
キーワード |
immune status |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
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キーワード |
young racing horse |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| 著者 |
バクタリ, マハマウド
WEKO
34853
| en |
Baakhtari, Mahmoud
|
| ja |
バクタリ, マハマウド
|
| ja-Kana |
バクタリ, マハマウド
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|
Search repository
Imaizumi, Noriko
Kida, Tetsuo
Yanagita, Tenya
Ramah, Amany
Ahmadi, Parnian
Takebe, Naoya
Iwamoto, Yohei
Korosue, Kenji
Tsuzuki, Nao
保田, 昌宏
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
High-intensity exercise and competition are associated with depressed immune function. Young horses, which participate in high-intensity exercise and competitions, are at increased risk for the development of infectious disease due to depression of immune function. The effects of branched-chain amino acid (BCAA) supplementation on the immune status of young racing horses were evaluated, determining whether BCAA might help to avoid or reduce immune suppression during exercise and competitions. Twenty horses (10 male and 10 female) were treated with BCAA supplementation; another twenty untreated horses (10 male and 10 female) constituted control group. Peripheral blood was collected from each animal and evaluated for lymphocyte subsets, phagocytosis analysis of monocytes and granulocytes, lymphocyte proliferative response, and expression of cytokine-encoding messenger ribonucleic acids (mRNAs). The numbers of CD4+, CD8+, and major histocompatibility complex (MHC) class II+ cells in females of the treated group were significantly higher than those in females of the control group. The lymphocyte proliferative response in female of the treated group also was significantly higher than that in females of the control group. In addition, expression of mRNAs encoding interleukin-1β (IL-1β) and interferon-γ (IFN-γ) in females of the treated group was significantly higher than that in females of the control group. There were no significant differences between males of the treated and control groups. The results of this study indicated the positive effects of BCAA supplementation in counteracting immunosuppression in young female racing horses during and following high-intensity exercise. |
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言語 |
en |
| 内容記述 |
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内容記述タイプ |
Other |
|
内容記述 |
Citation:
Baakhtari M, Imaizumi N, Kida T, Yanagita T, Ramah A, Ahmadi P, Takebe N, Iwamoto Y, Korosue K, Tsuzuki N, Yasuda M. Effects of branched-chain amino acids on immune status of young racing horses. J Vet Med Sci. 2022 Apr 15;84(4):558-565. doi: 10.1292/jvms.21-0529. Epub 2022 Feb 24. PMID: 35197413; PMCID: PMC9096041. |
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言語 |
en |
| 書誌情報 |
en : Journal of Veterinary Medical Science
巻 84,
号 4,
p. 558-565,
発行日 2022-04-15
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| 出版者 |
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出版者 |
Japanese Society of Veterinary Science |
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言語 |
en |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0916-7250 |
| DOI |
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関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1292/jvms.21-0529 |
| 権利 |
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言語 |
en |
|
権利情報 |
© 2022 by the Japanese Society of Veterinary Science |
| 著者版フラグ |
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出版タイプ |
VoR |
article (1.4 MB)
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