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Prediction of Posthepatectomy Liver Failure Proposed by the International Study Group of Liver Surgery : Residual Liver Function Estimation With 99mTc-Galactosyl Human Serum Albumin Scintigraphy
http://hdl.handle.net/10458/0002000168
http://hdl.handle.net/10458/0002000168f4046679-00e2-463d-b190-d3594c7d80d3
| 名前 / ファイル | ライセンス | アクション |
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著者原稿 (901 KB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2023-10-27 | |||||
| タイトル | ||||||
| タイトル | Prediction of Posthepatectomy Liver Failure Proposed by the International Study Group of Liver Surgery : Residual Liver Function Estimation With 99mTc-Galactosyl Human Serum Albumin Scintigraphy | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | 99mTc-GSA scintigraphy | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | liver failure | |||||
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| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | posthepatectomy | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
水谷, 陽一
× 水谷, 陽一× Hirai, Toshinori× 長町, 茂樹× 七島, 篤志× 矢野, 公一× 近藤, 千博× 旭吉, 雅秀× 今村, 直哉× 寺田, 珠沙 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | PURPOSE: The International Study Group of Liver Surgery (ISGLS) proposed a definition and grading system for posthepatectomy liver failure (PHLF). We evaluated the usefulness of residual liver function estimation using Tc-99m-galactosyl human serum albumin (99mTc-GSA) for the prediction of PHLF. METHODS: Patients with liver tumors (n = 136) and scheduled for hepatectomy underwent 99mTc-GSA scintigraphy. Based on their imaging data, the maximal GSA removal rate (GSA R-max）was calculated by multicompartment analysis. We also calculated GSA R-max in the predicted residual liver (GSA-RL) whose volume was determined on computed tomography (CT) scans. We compared the age, gender, 15-min indocyanine green retention rate, albumin-, bilirubin-, hyaluronic acid-, and type 4 collagen level, the Child-Pugh classification, residual liver volume, residual liver percentage, GSA R-max, and GSA-RL in patients with/without PHLF. Uni- and multivariate logistic analyses were used for statistical assessments. RESULTS: Of 136 patients, 17 (12.5%) met the ISGLS criteria for PHLF (ISGLS-PHLF). There was a statistically significant difference in the age, albumin level, Child-Pugh classification, residual liver volume, residual liver percentage, GSA R-max, and GSA-RL between patients with/without PHLF. Based on multivariate analysis, GSA-RL and the residual liver volume were significant independent predictors of ISGLS-PHLF (p = 0.004 and p = 0.038, respectively). The odds ratio was 149423 for GSA-RL and 1.003 for the residual liver volume. CONCLUSION: GSA-RL calculated by 99mTc -GSA scintigraphy was the most useful independent predictor for ISGLS-PHLF. |
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| 言語 | en | |||||
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| 内容記述タイプ | Other | |||||
| 内容記述 | Citation: Mizutani, Y., Hirai, T., Nagamachi, S., Nanashima, A., Yano, K., Kondo, K., Hiyoshi, M., Imamura, N., & Terada, T. (2018). Prediction of Posthepatectomy Liver Failure Proposed by the International Study Group of Liver Surgery: Residual Liver Function Estimation With 99mTc-Galactosyl Human Serum Albumin Scintigraphy. Clinical nuclear medicine, 43(2), 77–81. https://doi.org/10.1097/RLU.0000000000001913 |
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| 言語 | en | |||||
| 書誌情報 |
en : Clinical Nuclear Medicine 巻 43, 号 2, p. 77-81, 発行日 2018-02 |
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| 出版者 | ||||||
| 出版者 | Wolters Kluwer | |||||
| 言語 | en | |||||
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| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0363-9762 | |||||
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| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1097/rlu.0000000000001913 | |||||
| 権利 | ||||||
| 言語 | en | |||||
| 権利情報 | Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved. | |||||
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| 出版タイプ | AM | |||||
