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X-ray evaluation of intestinal dysmotility induced by Eimeria pragensis infection in C57BL/6 mice
http://hdl.handle.net/10458/0002000100
http://hdl.handle.net/10458/0002000100db0ae3fe-6c38-4999-8c07-ebd74c82d898
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
本文 (1.6 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2023-10-18 | |||||
| タイトル | ||||||
| タイトル | X-ray evaluation of intestinal dysmotility induced by Eimeria pragensis infection in C57BL/6 mice | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | barium gastrography | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | coccidiosis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | Eimeria pragensis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | intestinal dysmotility | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | pan-enteric ileus | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
シスワンヂィ, リキ
× シスワンヂィ, リキ× 吉田, 彩子× 佐藤, 裕之× 野中, 成晃 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | This study was conducted to elucidate the intestinal dysmotility during coccidiosis. C57BL/6 male mice at seven weeks of age were inoculated with Eimeria pragensis sporulated oocysts (100 to 1,000 oocysts). The intestinal motility was evaluated by observing discharging time of barium sulfate (Ba2SO4) after oral administration (WITT: the whole intestinal transit time). The exact location of the dysmotility was analyzed by intermittent barium gastrography. Upper intestinal dysmotility was evaluated by charcoal propulsion study. Additionally, the occurrence of dysmotility was observed at different post-infection times (4, 7, and 14 days post-infection (d.p.i.)) and in infection-dose dependent manner (100, 300, and 1,000 oocysts). As the E. pragensis infected mice had significantly lower feed intake compared to the control group, we designed a feed apprehension study to evaluate the effect of low feed intake on the intestinal dysmotility. The WITT of infected mice at 7 d.p.i. was significantly longer (6 hr) than the uninfected mice (2.5 hr). Intestinal dysmotility was observed in the small intestine, caecum, and colorectum in the infected mice. Charcoal propulsion was slower in infected group (reaching to 40.4% of the whole small intestine) compared to control group (68.0%). The dysmotility was observed at the beginning of the patent period (7 d.p.i.) and subsided as the patency ended (14 d.p.i.). Mice with lower feed intake appeared to have similar intestinal motility as control mice. In summary, this study revealed the evidence of intestinal hypomotility during E. pragensis infection. | |||||
| 言語 | en | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Citation: Riki SISWANDI, Ayako YOSHIDA, Hiroyuki SATOH, Nariaki NONAKA, X-ray evaluation of intestinal dysmotility induced by Eimeria pragensis infection in C57BL/6 mice, Journal of Veterinary Medical Science, 2019, Volume 81, Issue 7, Pages 1021-1028, Released on J-STAGE July 19, 2019, Advance online publication May 21, 2019, Online ISSN 1347-7439, Print ISSN 0916-7250, https://doi.org/10.1292/jvms.19-0137 |
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| 言語 | en | |||||
| 書誌情報 |
en : Journal of Veterinary Medical Science 巻 81, 号 7, p. 1021-1028, 発行日 2019-05-21 |
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| 出版者 | ||||||
| 出版者 | Japanese Society of Veterinary Science | |||||
| 言語 | en | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0916-7250 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1292/jvms.19-0137 | |||||
| 権利 | ||||||
| 言語 | en | |||||
| 権利情報 | © 2019 by the Japanese Society of Veterinary Science | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
