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  1. 医学部
  2. 学術雑誌掲載論文  (医学部)

Preferential localization of rat GAPDS on the ribs of fibrous sheath of sperm flagellum and its expression during flagellar formation

http://hdl.handle.net/10458/2348
http://hdl.handle.net/10458/2348
41d5f519-f3f5-46ad-bb7b-cc7e3950e415
名前 / ファイル ライセンス アクション
http___www.jstage.jst.go.pdf http___www.jstage.jst.go.pdf (633.7 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2009-10-08
タイトル
タイトル Preferential localization of rat GAPDS on the ribs of fibrous sheath of sperm flagellum and its expression during flagellar formation
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
キーワード fibrous sheath, flagellum, sperm, spermiogenesis, rat
資源タイプ
資源タイプ journal article
著者 Tanii, Ichiro

× Tanii, Ichiro

WEKO 8808

en Tanii, Ichiro

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Yagura, Tetsuya

× Yagura, Tetsuya

WEKO 8809

en Yagura, Tetsuya

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Inagaki, Naoyuki

× Inagaki, Naoyuki

WEKO 8810

en Inagaki, Naoyuki

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Nakayama, Tatsuo

× Nakayama, Tatsuo

WEKO 4839

en Nakayama, Tatsuo

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Imaizumi, Kazunori

× Imaizumi, Kazunori

WEKO 8738

en Imaizumi, Kazunori

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Yoshinaga, Kazuya

× Yoshinaga, Kazuya

WEKO 8813

en Yoshinaga, Kazuya

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抄録
内容記述タイプ Abstract
内容記述 The proper assembly of sperm flagellar proteins is fundamental for sperm motility. The sperm- and spermatid-specific isoform of glyceraldehyde 3-phosphate dehydrogenase, GAPDS, is a flagellar protein indispensable for sperm flagellar movement. To obtain information on the assembly of the glycolytic enzyme into the flagellum, the precise localization of rat GAPDS in the flagellum and the stage of incorporation into the flagellum were examined using a monoclonal antibody. Immunolocalization of rat GAPDS was restricted to the fibrous sheath (FS) in the sperm flagellum, and was predominant in the circumferential ribs rather than the longitudinal columns. Immunoreactivity was first detected in the cytoplasm and flagella of the step-16 spermatids during the final step of FS formation. Together with the expression of other FS proteins, the present results indicate the sequential assembly of FS components, suggesting that the expression and transport of GAPDS is regulated in a coordinated manner during sperm flagellar formation.
言語 en
内容記述
内容記述タイプ Other
内容記述 Copyright (c) 2007 By the Japan Society of Histochemistry and Cytochemistry
言語 en
書誌情報 en : Acta histochemica et cytochemica

巻 40, 号 1, p. 19-26, 発行日 2007
出版者
出版者 Japan Society of Histochemistry and Cytochemistry
言語 en
ISSN
収録物識別子タイプ ISSN
収録物識別子 00445991
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508022
著者版フラグ
出版タイプ VoR
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Ver.3 2023-07-29 23:10:04.738443
Ver.2 2023-07-29 07:45:23.880215
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Cite as

Tanii, Ichiro, Yagura, Tetsuya, Inagaki, Naoyuki, Nakayama, Tatsuo, Imaizumi, Kazunori, Yoshinaga, Kazuya, 2007, Preferential localization of rat GAPDS on the ribs of fibrous sheath of sperm flagellum and its expression during flagellar formation: Japan Society of Histochemistry and Cytochemistry, 19–26 p.

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