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Tonsillectomy Combined with Steroid Pulse Therapy Induces Clinical Remission of IgA Nephropathy
http://hdl.handle.net/10458/3707
http://hdl.handle.net/10458/3707685d771a-9843-493b-9737-216d5c0cafad
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
1471komatsu.pdf (233.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2012-05-30 | |||||
| タイトル | ||||||
| タイトル | Tonsillectomy Combined with Steroid Pulse Therapy Induces Clinical Remission of IgA Nephropathy | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
小松, 弘幸
× 小松, 弘幸× 藤元, 昭一 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Tonsillectomy combined with steroid pulse therapy has been a popular approach to treating IgA nephropathy （IgAN） in Japan for several years. However, little is understood about how such combined therapy affects the clinical course of IgAN. We therefore compared the effects of the combined therapy with those of steroid pulsing alone in a controlled study of patients with IgAN. The achievement ratio of clinical remission （CR）, defined as the disappearance of urinary protein （UP） and occult blood （UOB）, were compared between tonsillectomy combined with steroid pulse therapy （n=35） and steroid pulse monotherapy （n=20）. The CR rate was higher in the group given combined therapy than monotherapy at the final observation 54.0±21.2 months after the initial treatment （54.3 vs. 25.0%, p=0.033）. The Cox regression model showed that the combined therapy caused UP to disappear 6-fold more effectively than monotherapy. These findings suggest that tonsillectomy combined with steroid pulse therapy induces CR in patients with IgAN. Meanwhile, the indications for this therapy and verification of its positive long-term prognosis require urgent validation. | |||||
| 言語 | en | |||||
| 書誌情報 |
en : Advances in oto-rhino-laryngology 巻 72, p. 57-59, 発行日 2011 |
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| 出版者 | ||||||
| 出版者 | Karger | |||||
| 言語 | en | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 16622847 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 21865690 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1159/000324606 | |||||
| 権利 | ||||||
| 言語 | en | |||||
| 権利情報 | © 2012 S. Karger AG, Basel | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
