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Usefulness of carotid intima-media thickness measurement as an indicator of generalized atherosclerosis : Findings from autopsy analysis
http://hdl.handle.net/10458/5466
http://hdl.handle.net/10458/5466a9cb50ed-84ac-43c1-9a9d-714d6e9fe2cc
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2020-06-21 | |||||||
| タイトル | ||||||||
| タイトル | Usefulness of carotid intima-media thickness measurement as an indicator of generalized atherosclerosis : Findings from autopsy analysis | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| キーワード | Carotid intima-media thickness, Generalized atherosclerosis, Autopsy | |||||||
| 資源タイプ | ||||||||
| 資源タイプ | journal article | |||||||
| アクセス権 | ||||||||
| 著者 |
岩切, 太幹志
× 岩切, 太幹志× Yano, Yuichiro
× 佐藤, 勇一郎× 畠山, 金太× 丸塚, 浩助× 藤元, 昭一× 北村, 和雄× Kario, Kazuomi× 浅田, 祐士郎 |
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| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Background: Ultrasound-determined carotid intima-media thickness （IMT） is widely used as an indicator of generalized atherosclerotic burden, but there are limited autopsy findings in support of the association, directly. Methods: We performed an autopsy analysis （n = 111, mean 68.8 years; 65.0% men; 86% non-cardiovascular disease death） to examine the associations of microscopy-determined carotid IMT including plaque thickness with the severity of atherosclerosis in the generalized arteries. Results: Microscopy-determined carotid IMT was associated with the extent of intima/media layer ratio of the vasculature, a marker of atherosclerosis, in each structure examined, i.e., coronary artery, cerebrovasculature, thoracic aorta, abdominal aorta, and iliac artery （R = 0.31–0.42; all P < 0.01）. The prevalence of a necrotic core in the coronary artery, cerebrovasculature, thoracic aorta, abdominal aorta, and iliac artery increased in accordance with increasing microscopy-determined carotid IMT （all P < 0.05）. Conclusion: Our autopsy analysis confirms the validity of carotid IMT including plaque thickness as an indicator of generalized atherosclerosis. |
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| 言語 | en | |||||||
| 書誌情報 |
en : Atherosclerosis 巻 225, 号 2, p. 359–362-359–362, 発行日 2012-12 |
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| 出版者 | Elsevier | |||||||
| 言語 | en | |||||||
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| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 00219150 | |||||||
| DOI | ||||||||
| 関連タイプ | isVersionOf | |||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | https://doi.org/10.1016/j.atherosclerosis.2012.10.033 | |||||||
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| 出版タイプ | NA | |||||||
