@article{oai:miyazaki-u.repo.nii.ac.jp:00004617,
 author = {Iwakiri, Takashi and 岩切, 太幹志 and Yano, Yuichiro and Sato, Yuichiro and 佐藤, 勇一郎 and Hatakeyama, Kinta and 畠山, 金太 and 丸塚, 浩助 and Marutsuka, Kousuke and Fujimoto, Shouichi and 藤元, 昭一 and Kitamura, Kazuo and 北村, 和雄 and Kario, Kazuomi and Asada, Yujiro and 浅田, 祐士郎},
 issue = {2},
 journal = {Atherosclerosis},
 month = {Dec},
 note = {Background: Ultrasound-determined carotid intima-media thickness （IMT） is widely used as an indicator of generalized atherosclerotic burden, but there are limited autopsy findings in support of the association, directly.
Methods: We performed an autopsy analysis （n = 111, mean 68.8 years; 65.0% men; 86% non-cardiovascular disease death） to examine the associations of microscopy-determined carotid IMT including plaque thickness with the severity of atherosclerosis in the generalized arteries.
Results: Microscopy-determined carotid IMT was associated with the extent of intima/media layer ratio of the vasculature, a marker of atherosclerosis, in each structure examined, i.e., coronary artery, cerebrovasculature, thoracic aorta, abdominal aorta, and iliac artery （R = 0.31–0.42; all P < 0.01）. The prevalence of a necrotic core in the coronary artery, cerebrovasculature, thoracic aorta, abdominal aorta, and iliac artery increased in accordance with increasing microscopy-determined carotid IMT （all P < 0.05）.
Conclusion: Our autopsy analysis confirms the validity of carotid IMT including plaque thickness as an indicator of generalized atherosclerosis.},
 pages = {359–362--359–362},
 title = {Usefulness of carotid intima-media thickness measurement as an indicator of generalized atherosclerosis : Findings from autopsy analysis},
 volume = {225},
 year = {2012},
 yomi = {イワキリ, タカシ and サトウ, ユウイチロウ and ハタケヤマ, キンタ and マルツカ, コウスケ and フジモト, シヨウイチ and キタムラ, カズオ and アサダ　, ユウジロウ}
}