WEKO3
アイテム
{"_buckets": {"deposit": "3858e110-ad96-4322-9704-43cab165c67a"}, "_deposit": {"created_by": 5, "id": "266", "owner": "5", "owners": [5], "pid": {"revision_id": 0, "type": "depid", "value": "266"}, "status": "published"}, "_oai": {"id": "oai:miyazaki-u.repo.nii.ac.jp:00000266", "sets": ["26", "74"]}, "author_link": ["1076", "1071", "1077", "1074", "1078", "1073", "1075", "1079"], "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2003-05-22", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1-3", "bibliographicPageEnd": "112", "bibliographicPageStart": "108", "bibliographicVolumeNumber": "543", "bibliographic_titles": [{"bibliographic_title": "FEBS letters : for the rapid publication of short reports in biochemistry, biophysics and molecular biology", "bibliographic_titleLang": "en"}]}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Palytoxin (PTX) induces a cation channel through interaction\nwith Na+,K+-ATPase. It is unclear how this action relates to the enzyme\ncatalytic activity. We examined whether the action of PTX depends on\nthe catalytic domain specific for Na+,K+-ATPase. Wild-type\nNa+,K+-ATPase α-subunit (NNN) or its chimera (NCN), in which the\ncatalytic domain was replaced with that of SERCA, was co-expressed with\nβ-subunit in the yeast Saccharomyces cerevisiae. PTX (0.1-100 nM)\nincreased K+ efflux in NNN- or NCN-transfected cells to a similar degree\nbut not in non-transfected cells. When ouabain-resistant NNN and NCN\nwere expressed, PTX also increased K+ efflux. Ouabain inhibited the\neffect of PTX in NNN- or NCN-cells but not in ouabain-resistant cells.\nThese data suggest that the channel-forming action of PTX does not depend\non the catalytic domain species.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10001_description_6": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "\u003ca href=\"http://www.febsletters.com/\" target=\"_blank\"\u003eJournal HP\u003c/a\u003e", "subitem_description_language": "en", "subitem_description_type": "Other"}]}, "item_10001_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00642943", "subitem_source_identifier_type": "NCID"}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00145793", "subitem_source_identifier_type": "ISSN"}]}, "item_10001_text_25": {"attribute_name": "BIBID", "attribute_value_mlt": [{"subitem_text_value": "TC00000258"}]}, "item_10001_text_26": {"attribute_name": "登録日", "attribute_value_mlt": [{"subitem_text_value": "2008/01/30"}]}, "item_10001_textarea_24": {"attribute_name": "来歴", "attribute_value_mlt": [{"subitem_textarea_value": "Submitted by 勝昭 伊藤 (itokt@cc.miyazaki-u.ac.jp) on 2008-01-30T07:13:00Z\nNo. of bitstreams: 1\nFEBS543_108_2003.pdf: 117521 bytes, checksum: bb4470297e4d0c097980530e92000b3b (MD5)"}, {"subitem_textarea_value": "Approved for entry into archive by dspace dspace(lib-ir@of.miyazaki-u.ac.jp) on 2008-01-30T10:25:02Z (GMT) No. of bitstreams: 1\nFEBS543_108_2003.pdf: 117521 bytes, checksum: bb4470297e4d0c097980530e92000b3b (MD5)"}, {"subitem_textarea_value": "Made available in DSpace on 2008-01-30T10:25:02Z (GMT). No. of bitstreams: 1\nFEBS543_108_2003.pdf: 117521 bytes, checksum: bb4470297e4d0c097980530e92000b3b (MD5)\n Previous issue date: 2003-05-22"}]}, "item_10001_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifier": "", "affiliationNameIdentifierScheme": "ISNI", "affiliationNameIdentifierURI": "http://www.isni.org/isni/"}], "affiliationNames": [{"affiliationName": "", "affiliationNameLang": "ja"}]}], "creatorNames": [{"creatorName": "伊藤, 勝昭", "creatorNameLang": "ja"}, {"creatorName": "イトウ, カツアキ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Ito, Katsuaki", "creatorNameLang": "en"}], "familyNames": [{"familyName": "伊藤", "familyNameLang": "ja"}, {"familyName": "イトウ", "familyNameLang": "ja-Kana"}, {"familyName": "Ito", "familyNameLang": "en"}], "givenNames": [{"givenName": "勝昭", "givenNameLang": "ja"}, {"givenName": "カツアキ", "givenNameLang": "ja-Kana"}, {"givenName": "Katsuaki", "givenNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1071", "nameIdentifierScheme": "WEKO"}]}, {"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifier": "", "affiliationNameIdentifierScheme": "ISNI", "affiliationNameIdentifierURI": "http://www.isni.org/isni/"}], "affiliationNames": [{"affiliationName": "", "affiliationNameLang": "ja"}]}], "creatorNames": [{"creatorName": "伊藤, 勝昭", "creatorNameLang": "ja"}, {"creatorName": "イトウ, カツアキ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Ito, Katsuaki", "creatorNameLang": "en"}], "familyNames": [{"familyName": "伊藤", "familyNameLang": "ja"}, {"familyName": "イトウ", "familyNameLang": "ja-Kana"}, {"familyName": "Ito", "familyNameLang": "en"}], "givenNames": [{"givenName": "勝昭", "givenNameLang": "ja"}, {"givenName": "カツアキ", "givenNameLang": "ja-Kana"}, {"givenName": "Katsuaki", "givenNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1071", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Toyoda, Isao", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1073", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Higashiyama, Masato", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1074", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Uemura, Daisuke", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1075", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato, Masa H.", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1076", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshimura, Shige H.", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1077", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishii, Toshiaki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1078", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takeyasu, Kunio", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1079", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-06-21"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "FEBS543_108_2003.pdf", "filesize": [{"value": "117.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 117500.0, "url": {"label": "FEBS543_108_2003.pdf", "url": "https://miyazaki-u.repo.nii.ac.jp/record/266/files/FEBS543_108_2003.pdf"}, "version_id": "dea09636-b9f6-4f56-a6db-341f40a03159"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Palytoxin, Na+,K+-ATPase, Channel, Catalytic domain, Yeast, Chimera", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase", "subitem_title_language": "en"}]}, "item_type_id": "10001", "owner": "5", "path": ["74", "26"], "permalink_uri": "http://hdl.handle.net/10458/1131", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2008-01-30"}, "publish_date": "2008-01-30", "publish_status": "0", "recid": "266", "relation": {}, "relation_version_is_last": true, "title": ["Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase"], "weko_shared_id": 2}
Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase
http://hdl.handle.net/10458/1131
http://hdl.handle.net/10458/11311f7cd6cf-9337-4c94-ae67-7e3131da3b8f
名前 / ファイル | ライセンス | アクション |
---|---|---|
FEBS543_108_2003.pdf (117.5 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2008-01-30 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
キーワード | Palytoxin, Na+,K+-ATPase, Channel, Catalytic domain, Yeast, Chimera | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
伊藤, 勝昭
× 伊藤, 勝昭× 伊藤, 勝昭× Toyoda, Isao× Higashiyama, Masato× Uemura, Daisuke× Sato, Masa H.× Yoshimura, Shige H.× Ishii, Toshiaki× Takeyasu, Kunio |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Palytoxin (PTX) induces a cation channel through interaction with Na+,K+-ATPase. It is unclear how this action relates to the enzyme catalytic activity. We examined whether the action of PTX depends on the catalytic domain specific for Na+,K+-ATPase. Wild-type Na+,K+-ATPase α-subunit (NNN) or its chimera (NCN), in which the catalytic domain was replaced with that of SERCA, was co-expressed with β-subunit in the yeast Saccharomyces cerevisiae. PTX (0.1-100 nM) increased K+ efflux in NNN- or NCN-transfected cells to a similar degree but not in non-transfected cells. When ouabain-resistant NNN and NCN were expressed, PTX also increased K+ efflux. Ouabain inhibited the effect of PTX in NNN- or NCN-cells but not in ouabain-resistant cells. These data suggest that the channel-forming action of PTX does not depend on the catalytic domain species. |
|||||
言語 | en | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | <a href="http://www.febsletters.com/" target="_blank">Journal HP</a> | |||||
言語 | en | |||||
書誌情報 |
en : FEBS letters : for the rapid publication of short reports in biochemistry, biophysics and molecular biology 巻 543, 号 1-3, p. 108-112, 発行日 2003-05-22 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00145793 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00642943 | |||||
著者版フラグ | ||||||
出版タイプ | AM |