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Long-Term Survival of Patients with IgA Nephropathy After Dialysis Therapy
http://hdl.handle.net/10458/4811
http://hdl.handle.net/10458/48112136a5a9-881a-4a45-9678-c7faab296428
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
kmt_2013.pdf (886.3 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2014-04-02 | |||||
| タイトル | ||||||
| タイトル | Long-Term Survival of Patients with IgA Nephropathy After Dialysis Therapy | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | IgA nephropathy, Cardio-cerebrovascular diseases, End-stage kidney disease, Dialysis | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
小松, 弘幸
× 小松, 弘幸× 菊池, 正雄× 中川, 秀人× 福田, 顕弘× 岩切, 太幹志× 戸井田, 達典× 佐藤, 祐二× 北村, 和雄× 藤元, 昭一 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background/Aims: How dialysis affects the survival of patients with biopsy-proven IgA nephropathy （IgAN） is not fully understood. The present long-term cohort study quantifies the survival rates and incidence of cardio-cerebrovascular diseases （CCVDs） among such patients in Japan. Methods: Fifty-two of 433 patients with IgAN who had reached end-stage kidney disease underwent renal replacement therapy （RRT） between 1981 and 2010. The overall survival rate and incidence of CCVDs in these patients were evaluated during follow-up for 11.3 ± 6.4 years. Results: The mean age at starting RRT was 42.8 ± 13.3 years. Only seven patients died during follow-up （mortality rate, 1.2/100 person-years） and Kaplan-Meier analysis revealed favorable survival rates of 93.3% and 65.1% at 10 and 20 years, respectively, compared with that of patients with glomerulonephritis in the registry of the Japanese Society for Dialysis Therapy who required RRT. Malignancy and CCVDs were causes of death at 13.6 ± 4.8 and 3.9 ± 1.3 years, respectively, after starting RRT. Fatal and non-fatal CCVDs developed in 15 （incidence, 2.7/100 person-years） patients and acute coronary syndrome and cerebral hemorrhage developed relatively soon after starting RRT. Cox proportional hazards models revealed that age at the time of starting RRT was a significant factor affecting the onset of CCVDs. Meanwhile, a history of having had corticosteroid as an initial treatment did not affect the onset of events. Conclusion: Although the survival of patients with IgAN is favorable after dialysis, the onset of CCVDs during the early phase of dialysis should be carefully monitored. | |||||
| 言語 | en | |||||
| 書誌情報 |
en : Kidney and Blood Pressure Research 巻 37, 号 6, p. 649-656, 発行日 2013-12 |
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| 出版者 | ||||||
| 出版者 | Karger | |||||
| 言語 | en | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 14230143 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 24356555 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1159/000355745 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
