@article{oai:miyazaki-u.repo.nii.ac.jp:00001625,
 author = {Komatsu, Hiroyuki and 小松, 弘幸 and Kikuchi, Masao and 菊池, 正雄 and Nakagawa, Hideto and 中川, 秀人 and Fukuda, Akihiro and 福田, 顕弘 and Iwakiri, Takashi and 岩切, 太幹志 and Toida, Tatsunori and 戸井田, 達典 and Sato, Yuji and 佐藤, 祐二 and Kitamura, Kazuo and 北村, 和雄 and Fujimoto, Shouichi and 藤元, 昭一},
 issue = {6},
 journal = {Kidney and Blood Pressure Research},
 month = {Dec},
 note = {Background/Aims: How dialysis affects the survival of patients with biopsy-proven IgA nephropathy （IgAN） is not fully understood. The present long-term cohort study quantifies the survival rates and incidence of cardio-cerebrovascular diseases （CCVDs） among such patients in Japan. Methods: Fifty-two of 433 patients with IgAN who had reached end-stage kidney disease underwent renal replacement therapy （RRT） between 1981 and 2010. The overall survival rate and incidence of CCVDs in these patients were evaluated during follow-up for 11.3 ± 6.4 years. Results: The mean age at starting RRT was 42.8 ± 13.3 years. Only seven patients died during follow-up （mortality rate, 1.2/100 person-years） and Kaplan-Meier analysis revealed favorable survival rates of 93.3% and 65.1% at 10 and 20 years, respectively, compared with that of patients with glomerulonephritis in the registry of the Japanese Society for Dialysis Therapy who required RRT. Malignancy and CCVDs were causes of death at 13.6 ± 4.8 and 3.9 ± 1.3 years, respectively, after starting RRT. Fatal and non-fatal CCVDs developed in 15 （incidence, 2.7/100 person-years） patients and acute coronary syndrome and cerebral hemorrhage developed relatively soon after starting RRT. Cox proportional hazards models revealed that age at the time of starting RRT was a significant factor affecting the onset of CCVDs. Meanwhile, a history of having had corticosteroid as an initial treatment did not affect the onset of events. Conclusion: Although the survival of patients with IgAN is favorable after dialysis, the onset of CCVDs during the early phase of dialysis should be carefully monitored.},
 pages = {649--656},
 title = {Long-Term Survival of Patients with IgA Nephropathy After Dialysis Therapy},
 volume = {37},
 year = {2013},
 yomi = {コマツ, ヒロユキ and キクチ, マサオ and ナカガワ, ヒデト and フクダ, アキヒロ and イワキリ, タカシ and トイダ, タツノリ and サトウ, ユウジ and キタムラ, カズオ and フジモト, シヨウイチ}
}