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Effects of refeeding diets on emeriamine-induced fatty liver in fasting rats
http://hdl.handle.net/10458/3530
http://hdl.handle.net/10458/353047f5f44e-753c-43fc-ba18-98e0d012247e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
FN_868.pdf (1.1 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2011-12-02 | |||||
| タイトル | ||||||
| タイトル | Effects of refeeding diets on emeriamine-induced fatty liver in fasting rats | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| キーワード | dietary composition, emeriamine, fatty acid, glycogen, fatty liver, high-carbohydrate diet, high-fat diet, triglyceride | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Maeda, Hideo
× Maeda, Hideo× Fujiwara, Miho× Miyamoto, Kana× Hamamoto, Hidetoshi× Fukuda, Nobuhiro |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We recently reported that fatty liver and hypertriglyceridemia are easily induced by the administration of an inhibitor of fatty acid oxidation （emeriamine; （R）-3-amino-4-trimethylaminobutyric acid） to fasting rats, and that these conditions are not accompanied by the increased de novo synthesis of fatty acid [J. Nutr. Sci. Vitaminol., 42, 111-120, （1996）]. To study whether emeriamine-induced fatty liver is affected by nutrients during recovery from fatty acid oxidation inhibition, we fed rats with either a high-carbohydrate （HCHO） diet or a high-fat （HFAT） diet. Rats fed an HCHO diet following the administration of emeriamine showed a marked decrease in serum and hepatic triglycerides, and a marked increase in hepatic glycogen. The lower levels of serum and hepatic triglycerides were accompanied by decreased activities of the NADPH-generating enzymes such as malic enzyme and glucose-6-phosphate dehydrogenase. By contrast, rats fed an HFAT diet showed less significant changes in hepatic triglyceride and glycogen levels. These results suggest a reciprocal relationship between the triglyceride level and glycogen accumulation caused by HCHO diet during recovery from emeriamine. | |||||
| 言語 | en | |||||
| 書誌情報 |
en : Journal of Nutritional Science and Vitaminology 巻 42, 号 5, p. 469-478, 発行日 1996-10 |
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| 出版者 | ||||||
| 出版者 | The Vitamin Society of Japan | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | 日本ビタミン学会 | |||||
| 言語 | ja | |||||
| 出版者 | ||||||
| 出版者 | University of Tokyo Press | |||||
| 言語 | en | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 03014800 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00703822 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 8981252 | |||||
| 権利 | ||||||
| 言語 | ja | |||||
| 権利情報 | 日本ビタミン学会 | |||||
| 権利 | ||||||
| 言語 | ja | |||||
| 権利情報 | 本文データは学協会の許諾に基づきJournal@rchiveから複製したものである | |||||
| 他の資源との関係 | ||||||
| 関連名称 | http://dx.doi.org/10.3177/jnsv.42.469 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
