@article{oai:miyazaki-u.repo.nii.ac.jp:00000772,
 author = {黄, 莉 and 池尻, 藍 and 清水, 佑也 and 足立, 匠 and 後藤, 義孝 and Goto, Yoshitaka and 外山, 潤 and 田中, 秀典 and Tanaka, Hidenori and 明石, 良 and Akashi, Ryo and 内田, 和幸 and Uchida, Kazuyuki and 宮田, 博規 and 芳賀, 猛 and Haga, Takeshi and Huang, Li and Ikejiri, Ai and Shimizu, Yuya and Adachi, Takumi and Toyama, Jun and Miyata, Hironori},
 issue = {5},
 journal = {The journal of veterinary medical science, Journal of veterinary medical science},
 month = {May},
 note = {The aim of this study is to investigate the immunoadjuvant activity of the crude Momordica charantia lectin （crMCL） extracted from seed using β-galactosidase （β-gal） as the model antigen. BALB/c mice were injected intramuscularly with β-gal alone or β-gal + crMCL for up to four immunizations at two-week intervals. After administration of 2 doses, the IgG-specific titer to β-gal was significantly higher in mice in the β-gal + crMCL group than in that from the animals from the β-gal alone group, while it was about the same in both groups after 1 dose. Our data suggest that crMCL may help raise antibodies under the prime and boost administration regimen and could be a potent vaccine adjuvant., ニガウリ種子由来粗精製レクチン（CrMCL）のアジュバント効果について,ベータガラクトシダーゼをモデル抗原として解析した.BALB/cマウスを抗原単独投与群と抗原+CrMCL投与群に分け,血清中の抗原特異的IgG抗体価を測定したところ,1回免疫では両群で差がなかったが,追加免疫で抗原+crMCL投与群が有意に高かった. CrMCLはプライムブースト投与法に有用なアジュバントであることが示唆された.},
 pages = {533--535},
 title = {Immunoadjuvant activity of crude lectin extracted from Momordica charantia seed},
 volume = {70},
 year = {2008},
 yomi = {ホー, リー and イケジリ, アイ and シミズ, ユウヤ and アダチ, タクミ and ゴトウ, ヨシタカ and トヤマ, ジュン and タナカ, ヒデノリ and アカシ, リョウ and ウチダ, カズユキ and ミヤタ, ヒロノリ and ハガ, タケシ}
}