{"created":"2023-05-15T10:01:28.248294+00:00","id":6057,"links":{},"metadata":{"_buckets":{"deposit":"f3de85bf-54a1-43de-8238-1712c0d76880"},"_deposit":{"created_by":5,"id":"6057","owner":"5","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"6057"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00006057","sets":["80","80:65"]},"author_link":["2630","7810","32286","32287"],"item_10010_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-06","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"64","bibliographicPageStart":"62","bibliographic_titles":[{"bibliographic_title":"5th International Arsenic Symposium in MIYAZAKI 2018","bibliographic_titleLang":"en"}]}]},"item_10010_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Contamination of drinking water by arsenic metabolites, which can occur naturally or due to human activities such as mining and industrialization, is an important public health issue in south Asia. More than 200 million are exposed to arsenic through drinking water. Chronic exposure to this metalloid has been associated with onset of many diseases, including cancer. There are 4 major molecular mechanisms through which arsenic disturbs cell health. They are （1） Arsenic contaminated water disturbs the gastric mucosal barrier thereby altering the cell stress hemostasis （2） Tt directly or indirectly interacts with energy synthesis pathway and induces cellular ROS generation （3） Tt inhibits the repair machinery （4） Finally, arsenic induces DNA abnormality. Understanding the molecular mechanisms of arsenic exposure and its subsequent health effects at cellular level will support efforts to reduce the worldwide health burden and encourage the development of strategies for managing arsenic-related diseases in the era of personalized medicine.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10010_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"University of Miyazaki, IRISH","subitem_publisher_language":"en"}]},"item_10010_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"0000000106573887","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/0000000106573887"}],"affiliationNames":[{"affiliationName":"宮崎大学","affiliationNameLang":"ja"},{"affiliationName":"University of Miyazaki","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Madhyastha, Harishkumar","creatorNameLang":"en"},{"creatorName":"マドゥエスタ, ハリーシャクマール","creatorNameLang":"ja"},{"creatorName":"マドゥエスタ, ハリーシャクマール","creatorNameLang":"ja-Kana"},{"creatorName":"Madhyastha, Harish 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マスギ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Maruyama","familyNameLang":"en"},{"familyName":"丸山","familyNameLang":"ja"},{"familyName":"マルヤマ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Masugi","givenNameLang":"en"},{"givenName":"眞杉","givenNameLang":"ja"},{"givenName":"マスギ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2630","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-22"}],"displaytype":"detail","filename":"5th_int_p62.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","url":"https://miyazaki-u.repo.nii.ac.jp/record/6057/files/5th_int_p62.pdf"},"version_id":"5bd62cc6-dc6d-434d-83b2-a473cafc1335"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Arsenic, 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analysis"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2025-01-16T05:28:55.356613+00:00"}