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Sensory disturbance and electrophysiological findings in patients with chronic arsenic intoxication in Toroku, Japan: A 40-year follow-up study
http://hdl.handle.net/10458/6892
http://hdl.handle.net/10458/68920e76bb47-484f-4538-9f59-f3e4e4b64759
| 名前 / ファイル | ライセンス | アクション |
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本文 (1.6 MB)
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| Item type | その他 / Others(1) | |||||
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| 公開日 | 2020-06-22 | |||||
| タイトル | ||||||
| タイトル | Sensory disturbance and electrophysiological findings in patients with chronic arsenic intoxication in Toroku, Japan: A 40-year follow-up study | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Arsenic, chronic arsenic intoxication, neurological findings, electrophysiological study | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_1843 | |||||
| 資源タイプ | other | |||||
| 著者 |
石井, 信之
× 石井, 信之× Mochizuki, Hitoshi× 海老原, 由佳× 塩見, 一剛× 中里, 雅光 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Chronic arsenic intoxication is known to cause multisystem impairment including sensory dysfunction, and is still a major threat to public health in many countries. Tn Toroku, a small village in Japan, arsenic mines operated from 1920 to 1962, and residents suffered serious sequelae of chronic arsenic intoxication. We have performed annual medical examinations of these patients since 1974, allowing us to characterize patients' long-term health following their last exposure to arsenic. We have evaluated the longitudinal analysis of sensory dysfunction by neurological examination and nerve conduction study. The severity of both superficial and deep sensation worsened significantly over time （P=0.04 and P<0.01, respectively）, although nerve conduction velocities of sensory nerves in the lower extremities significantly improved （P<0.01）. This is the first study characterizing the longitudinal sequelae of sensory impairment after chronic arsenic exposure. Our study will be helpful in assessing the prognosis of patients worldwide who still suffer from chronic arsenic intoxication. | |||||
| 言語 | en | |||||
| 書誌情報 |
en : 5th International Arsenic Symposium in MIYAZAKI 2018 p. 56-60, 発行日 2018-06 |
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| 出版者 | ||||||
| 出版者 | University of Miyazaki, IRISH | |||||
| 言語 | en | |||||
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| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
