@article{oai:miyazaki-u.repo.nii.ac.jp:00005643,
 author = {松本, 仁 and 鈴木, 巧 and 松本, 朋子 and Matsumoto, Tomoko and 保田, 昌秀 and Yasuda, Masahide and Mastumoto, Jin and Suzuki, Kou},
 journal = {宮崎大学工学部紀要, Memoirs of Faculty of Engineering, University of Miyazaki},
 month = {Jul},
 note = {Porphyrins have received substantial attention in developing singlet oxygen (1O2) sensitizers for the photoinactivation of bacteria and for the photodynamic therapy (PDT) of tumor cells. Binding affinity of 1O2-sensitizer towards biomolecules such as DNA, protein, and saccharides is important for these biological applications. Especially, since cancer cells have a tendency to accumulate saccharides, the binding affinity of 1O2-sensitizer to tumor cells can be often enhanced by endowing the affinity towards saccharides. Here, we designed Sb-porphyrins (1a) incorporated axially with phenylboronic acid group, which can usually interact with cis-diol of saccharides. Actually the presence of glucose (3a), fructose (3b), and galactose (3c) caused to the spectral changes in absorption and fluorescence spectra as well as mass spectrometry of 1a due to the formation of an aggregate between 1a and 3. The binding constant (K) for the 1a–3b adduct were measured to be 1.39×10^5, 3.1×10^3, and 1.7×10^3 M^−1 by analysis of the absorption and the fluorescence spectral changes and the mass spectrometry, respectively. It was thought that the difference of these K values is dependent on the structure of the aggregates. Thus, it was found that 1a can highly associate with saccharides.},
 pages = {1--6},
 title = {ボロン酸置換ポルフィリンの糖認識特性},
 volume = {47},
 year = {2018},
 yomi = {マツモト, ジン and スズキ, コウ and マツモト, トモコ and ヤスダ, マサヒデ}
}