{"created":"2023-05-15T09:56:49.306180+00:00","id":521,"links":{},"metadata":{"_buckets":{"deposit":"dffc5df8-363d-4ad1-bd5b-11266f557353"},"_deposit":{"created_by":5,"id":"521","owner":"5","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"521"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00000521","sets":["74","74:26"]},"author_link":["1806","1808","3038","788","1255","3041"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2001","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"242","bibliographicPageStart":"234","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"Journal of pineal research","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Chick pineal cells have photoreceptive, circadian clock and melatonin synthetic capacities, and express circadian oscillation of melatonin release in vitro. Light pulses cause phase-dependent phase shift of the melatonin rhythm. The purpose of this study was to address the questions whether intracellular calcium is involved in both light-induced phase advance and delay. Thapsigargin and cyclopiazonic acid, which deplete the intracellular calcium stores, blocked the light-induced phase advance in a dose-dependent manner. The pulses of ryanodine receptor antagonist （dantrolene sodium or ruthenium red） also blocked the light-induced phase advance. Most agents did not cause a significant phase shift by themselves. On the other hand, all the agents used, failed to block the light-induced phase delay, even if the magnitude of phase delay was decreased using low intensity light. An antagonist of nitric oxide synthase blocked neither light-induced phase advance nor phase delay. These results indicate the following possibilities: （1） the mechanism of light-induced phase advance and delay may be different in chick pineal cells, or （2） if intracellular calcium is involved in both light-induced phase advance and delay, the sensitivity to light and/or agents used in this study may differ according to Zeitgeber time.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Blackwell Publishing","subitem_publisher_language":"en"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10641255","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"07423098","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"1600079X","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakahara, Keiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1806","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90315359","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90315359"}]},{"creatorNames":[{"creatorName":"Murakami, Noboru","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1808","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takigami, Eri","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3038","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nasu, Tetsuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"788","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Murakami, Takayuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1255","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shiota, Kunio","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3041","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"displaytype":"detail","filename":"jpr30-4.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jpr30-4.pdf","url":"https://miyazaki-u.repo.nii.ac.jp/record/521/files/jpr30-4.pdf"},"version_id":"eb301606-7b17-4105-b8a4-406f2a3142ce"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Circadian rhythms, Melatonin, Pineal cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Intracellular Ca2+ signaling pathway is involved in light-induced phase advance, but may not be in phase delay, of the circadian melatonin rhythm in chick pineal cell","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Intracellular Ca2+ signaling pathway is involved in light-induced phase advance, but may not be in phase delay, of the circadian melatonin rhythm in chick pineal cell","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"5","path":["74","26"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-03-02"},"publish_date":"2009-03-02","publish_status":"0","recid":"521","relation_version_is_last":true,"title":["Intracellular Ca2+ signaling pathway is involved in light-induced phase advance, but may not be in phase delay, of the circadian melatonin rhythm in chick pineal cell"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2023-07-29T13:36:11.544807+00:00"}