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Effects of daily injections of melatonin on locomotor activity rhythms in rats maintained under constant bright or dim light
http://hdl.handle.net/10458/1869
http://hdl.handle.net/10458/18696d5f04a9-6390-40ef-b2bb-e336be6545e0
| 名前 / ファイル | ライセンス | アクション |
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pb60-3.pdf (928.9 kB)
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| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2009-02-26 | |||||
| タイトル | ||||||
| タイトル | Effects of daily injections of melatonin on locomotor activity rhythms in rats maintained under constant bright or dim light | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| キーワード | Circadian rhythm, Melatonin, Pineal gland | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
丸本, 信之
× 丸本, 信之× Murakami, Noboru× Katayama, Tetsuo× Kuroda, Haruto× Murakami, Takayuki |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | It has been demonstrated that daily melatonin injections entrain free-running locomotor activity rhythms in rats kept in constant darkness, and synchronize disrupted circadian patterns of wheel-running activity under constant light. Contrary to these previous observations, our result did not show that daily injections of melatonin synchronize disrupted locomotor activity in rats maintained under constant bright light. On the other hand, daily treatment with melatonin entrained the intact free-running rhythm in rats kept in constant dim light. This entrainment took place only when the time of injection corresponded to the activity onset time, and similar results were obtained in blinded rats. Pinealectomy had no influences on either the free-running rhythm or melatonin-induced entrainment. To examine whether a behavioral feedback mechanism is involved in melatonin-induced entrainment, rats were immobilized for 3 h after each daily melatonin injections. This did not interfere with melatonin-induced entrainment. These results suggest that the mechanism underlying melatonin-induced entrainment of activity rhythms may be different from those in photic and behavioral entrainment. | |||||
| 言語 | en | |||||
| 書誌情報 |
en : Physiology and behavior : an international journal 巻 60, 号 3, p. 767-773, 発行日 1996-09 |
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| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| 言語 | en | |||||
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| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00319384 | |||||
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| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00352932 | |||||
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| 出版タイプ | AM | |||||
