{"created":"2023-05-15T10:00:15.874533+00:00","id":4582,"links":{},"metadata":{"_buckets":{"deposit":"f2d37a58-b819-483f-b1f6-d733526fdaaa"},"_deposit":{"created_by":5,"id":"4582","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"4582"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00004582","sets":["72","72:30"]},"author_link":["9050","9110","24524","9053","24662","24528","24680","24652","24664","24525","8704","8383"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-09","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"103–108","bibliographicPageStart":"103–108","bibliographicVolumeNumber":"126","bibliographic_titles":[{"bibliographic_title":"Pharmacology Biochemistry and Behavior"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objectives:We examined the effects of two dopamine agonists, cabergoline and rotigotine, on tacrine-induced tremor and c-Fos expression in rats.\nMethods:Rats received intraperitoneal injection of cabergoline （0.5, 1.0, or 5.0 mg/kg）, rotigotine （1.0, 2.5, or 10.0 mg/kg）, or vehicle 30 min before intraperitoneal injection of tacrine （5.0 mg/kg）. The number of tremulous jaw movements （TJMs） after tacrine administration was counted for 5 min. Animals were sacrificed 2 h later under deep anesthesia, and the brain sections were immunostained in order to evaluate the c-Fos expression.\nResults:Induction of TJMs by tacrine was dose-dependently reduced by pretreatment with cabergoline and rotigotine. The number of c-Fos-positive cells was significantly enhanced in the medial striatum, nucleus accumbens core, and nucleus accumbens shell after tacrine administration, and the enhanced expression of c-Fos in these three regions was significantly attenuated by cabergoline, while rotigotine suppressed c-Fos expression in two regions except the nucleus accumbens core.\nConclusions:These results suggest that tacrine-induced TJMs would be relieved by either cabergoline or rotigotine and that anticholinesterase-induced TJMs and the ameliorating effects of dopamine agonists would relate to neuronal activation in the striatum and nucleus accumbens.","subitem_description_type":"Abstract"}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"学位論文の一部を構成しているため、http://hdl.handle.net/10458/5430 に本文を掲載。","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://hdl.handle.net/10458/5430"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://hdl.handle.net/10458/5430","subitem_relation_type_select":"HDL"}}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00913057","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"小金丸, 剛","creatorNameLang":"ja"},{"creatorName":"コガネマル, ゴウ","creatorNameLang":"ja-Kana"},{"creatorName":"Koganemaru, Go","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"安部, 博史","creatorNameLang":"ja"},{"creatorName":"アベ, ヒロシ","creatorNameLang":"ja-Kana"},{"creatorName":"Abe, Hiroshi","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"倉増, 亜紀","creatorNameLang":"ja"},{"creatorName":"クラマシ, アキ","creatorNameLang":"ja-Kana"},{"creatorName":"Kuramashi, 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寿栄","creatorNameLang":"ja"},{"creatorName":"マツオ, ヒサエ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"船橋, 英樹"},{"creatorName":"フナハシ, ヒデキ","creatorNameLang":"ja-Kana"},{"creatorName":"Funahashi, Hideki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"保田, 和哉"},{"creatorName":"ヤスダ, カズヤ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"池田, 哲也","creatorNameLang":"ja"},{"creatorName":"イケダ, テツヤ","creatorNameLang":"ja-Kana"},{"creatorName":"Ikeda, 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ヒロシ","creatorNameLang":"ja-Kana"},{"creatorName":"Abe, Hiroshi","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"倉増, 亜紀","creatorNameLang":"ja"},{"creatorName":"クラマシ, アキ","creatorNameLang":"ja-Kana"},{"creatorName":"Kuramashi, Aki","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"蛯原, 功介","creatorNameLang":"ja"},{"creatorName":"エビハラ, コウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Ebihara, Kosuke","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Matsuo, Hisae","creatorNameLang":"en"},{"creatorName":"松尾, 寿栄","creatorNameLang":"ja"},{"creatorName":"マツオ, ヒサエ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yasuda, Kazuya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"池田, 哲也","creatorNameLang":"ja"},{"creatorName":"イケダ, テツヤ","creatorNameLang":"ja-Kana"},{"creatorName":"Ikeda, Tetsuya","creatorNameLang":"en"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishimori, Toshikazu","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Cabergoline, Rotigotine, Tacrine, Tremulous jaw movement, c-Fos, Parkinsonism","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of cabergoline and rotigotine on tacrine-induced tremulous jaw movements in rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of cabergoline and rotigotine on tacrine-induced tremulous jaw movements in rats","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"5","path":["72","30"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-06-21"},"publish_date":"2020-06-21","publish_status":"0","recid":"4582","relation_version_is_last":true,"title":["Effects of cabergoline and rotigotine on tacrine-induced tremulous jaw movements in rats"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2024-01-30T04:27:02.506653+00:00"}