{"created":"2023-05-15T09:59:48.860124+00:00","id":4034,"links":{},"metadata":{"_buckets":{"deposit":"9ab1e8d5-40e6-4dba-9f29-70cafbd19e95"},"_deposit":{"created_by":5,"id":"4034","owner":"5","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"4034"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00004034","sets":["74","74:58"]},"author_link":["1787"],"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"今回,生理活性機能として肝臓加水分解物中に存在が期待される血圧上昇を抑制するACE阻害活性と多くの疾病に関与しているラジカルに対する消去活性を測定した｡\nその結果、レバーHiのACE阻害活性は他のACE阻害ペプチドの粗精製品よりも比較的高い活性を有していることが明らかになった。また,さらにレバーHiをエタノール分画した結果, レバーHi中のACE阻害活性は低分子量域に存在するペプチドにより高い活性が発揮されることも認められた。今後,それらの高い活性を有するペプチドの単離･精製を進めて,レバーHi中のACE阻害ペプチドの構造解析を行う必要がある。\n一方、肝臓の酵素分解ペプチドの抗酸化活性の有無について検討する目的で,DPPH分光測定法と安息香酸ヒドロキシル化法による分析を行った。その結果,レバーHi標品は抗酸化活性を有していることも明らかになった。レバーHiは高い肝機能改善効果を有することからそれらの機能性成分の検索をさらに追及する予定である。こいずれにしても,レバーHiは酵素分解された低分子ペプチドからなるために,消化性および吸収性に優れ,高齢者や乳幼児のための健康食品として,あるいは病人のみならず健常人やスポーツ選手の体力増強食品素材として高度で幅広い利用が期待できる｡","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_10007_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"この研究は「伊藤記念財団」の助成を受けて行われました。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10007_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"displaytype":"detail","filename":"1312muguruma.pdf","filesize":[{"value":"451.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"1312muguruma.pdf","url":"https://miyazaki-u.repo.nii.ac.jp/record/4034/files/1312muguruma.pdf"},"version_id":"f1e66ded-9439-47ce-9f1d-190b532607ba"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"https://isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"六車, 三治男","creatorNameLang":"ja"},{"creatorName":"ムグルマ, ミチオ","creatorNameLang":"ja-Kana"},{"creatorName":"Muguruma, Michio","creatorNameLang":"en"}],"familyNames":[{"familyName":"六車","familyNameLang":"ja"},{"familyName":"ムグルマ","familyNameLang":"ja-Kana"},{"familyName":"Muguruma","familyNameLang":"en"}],"givenNames":[{"givenName":"三治男","givenNameLang":"ja"},{"givenName":"ミチオ","givenNameLang":"ja-Kana"},{"givenName":"Michio","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1787","nameIdentifierScheme":"WEKO"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"肝臓酵素分解物の新規生理活性機能の検索","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"肝臓酵素分解物の新規生理活性機能の検索","subitem_title_language":"ja"},{"subitem_title":"Search of Novel Biologically Active Components in Liver Hydrolysates","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"5","path":["74","58"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2012-07-17"},"publish_date":"2012-07-17","publish_status":"0","recid":"4034","relation_version_is_last":true,"title":["肝臓酵素分解物の新規生理活性機能の検索"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2024-12-06T07:39:35.753867+00:00"}