{"created":"2023-05-15T09:59:40.443167+00:00","id":3870,"links":{},"metadata":{"_buckets":{"deposit":"1701567a-37da-4473-ae71-c18ec9ac3d0a"},"_deposit":{"created_by":9,"id":"3870","owner":"9","owners":[9],"pid":{"revision_id":0,"type":"depid","value":"3870"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00003870","sets":["72","72:54"]},"author_link":["9832"],"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2014-03-24"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"宮崎大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17601","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)","subitem_degreename_language":"ja"}]},"item_10006_description_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_description":"2013年度","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[Background/Purpose] Previous FDG-PET studies have indicated neuroplasticity in the adult auditory cortex in cases of postlingual deafness. In the mature brain, auditory deprivation decreased neuronal activity in primary auditory and auditory-related cortices. In order to reevaluate these issues, we used statistical analytic software, three-dimensional stereotaxic region of interest (ROI) template (3DSRT), in addition to statistical parametric mapping (SPM).\n[Materials and Methods] 18F-FDG brain PET scans were performed on 7 postlingually deaf patients and 10 healthy volunteers. Significant increases and decreases of regional cerebral glucose metabolism in the patient group were estimated by comparing their PET images with those of the healthy volunteers using SPM analysis and 3DSRT.\n[Results] The glucose metabolism of deaf patients was found to be lower than that of the control subjects in the right superior temporal gyrus, both middle temporal gyri, left inferior temporal gyrus, right lobule parietalis inferior, and left insular cortex by SPM. 3DSRT data also revealed significantly decreased glucose metabolism in both primary auditory cortices in postlingually deaf patients.\n[Conclusion] SPM and 3DSRT analyses indicated that glucose metabolism decreases in the primary auditory cortex of postlingually deaf patients. The previous results of PET studies were confirmed. Our method involving 3DSRT is useful.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"医博乙第50号"}]},"item_10006_textarea_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"本論文に関連する研究論文\nOkuda T, Nagamachi S, Ushisako Y, Tono T. Glucose metabolism in the primary auditory cortex of postlingually deaf patients: an FDG-PET study. ORL J Otorhinolaryngol Relat Spec. 2013;75(6):342-9. doi: 10.1159/000357474. Epub 2014 Jan 10. PMID: 24435067."}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Okuda, Takumi","creatorNameLang":"en"},{"creatorName":"奥田, 匠","creatorNameLang":"ja"},{"creatorName":"オクダ, タクミ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Okuda","familyNameLang":"en"},{"familyName":"奥田","familyNameLang":"ja"},{"familyName":"オクダ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Takumi","givenNameLang":"en"},{"givenName":"匠","givenNameLang":"ja"},{"givenName":"タクミ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"9832","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60404456","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=60404456"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"filename":"B50Yhakuron.pdf","filesize":[{"value":"106.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"論文要旨","objectType":"abstract","url":"https://miyazaki-u.repo.nii.ac.jp/record/3870/files/B50Yhakuron.pdf"},"version_id":"767effe0-350b-4fa8-a37a-14f164673c8f"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"filename":"B50Yshinsa.pdf","filesize":[{"value":"69.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"学位論文審査結果の要旨","objectType":"other","url":"https://miyazaki-u.repo.nii.ac.jp/record/3870/files/B50Yshinsa.pdf"},"version_id":"23825ed7-bdf1-4b16-aea4-e20e5c398f3a"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"displaytype":"detail","filename":"B50Honbun.pdf","filesize":[{"value":"6.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"博士学位論文","objectType":"fulltext","url":"https://miyazaki-u.repo.nii.ac.jp/record/3870/files/B50Honbun.pdf"},"version_id":"151ec149-8270-420f-8884-882b102912ce"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"FDG-PET, neuroplasticity, auditory cortex, deafness","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Glucose metabolism in primary auditory cortex of postlingually deaf patients : FDG-PET study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Glucose metabolism in primary auditory cortex of postlingually deaf patients : FDG-PET study","subitem_title_language":"en"},{"subitem_title":"言語習得後失聴者における一次聴覚野でのグルコース代謝 : FDG-PETによる評価","subitem_title_language":"ja"}]},"item_type_id":"10006","owner":"9","path":["72","54"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-06-09"},"publish_date":"2014-06-09","publish_status":"0","recid":"3870","relation_version_is_last":true,"title":["Glucose metabolism in primary auditory cortex of postlingually deaf patients : FDG-PET study"],"weko_creator_id":"9","weko_shared_id":-1},"updated":"2024-02-09T07:56:58.392939+00:00"}