@article{oai:miyazaki-u.repo.nii.ac.jp:00000359, author = {Inoue, Yo and 村上, 昇 and Murakami, Noboru and 堀井, 洋一郎 and Horii, Yoichiro and Rivero, Juan C. and Inoue, Yo and Rivero, J.C.}, issue = {6}, journal = {The journal of veterinary medical science}, month = {Jun}, note = {The effects of host age and sex on susceptibility to Strongyloides venezuelensis in Wistar rats were examined by counting larvae recovered from the lungs of animals 3 days after infection. The susceptibility of female rats to S. venezuelensis rapidly decreased with age and elevated estrogen. Resistance in female rats inoculated at 6 and 10 weeks of age was nine and twenty-fold higher, respectively than that in the youngest group (3 weeks). In contrast, the susceptibility of male animals was lowest in the youngest group, then increased with age and elevated testosterone. Sex differences in susceptibility were not evident in the youngest group, but became apparent with age., ウィスターラットの週齢および性差がベネズエラ糞線虫の感染感受性に及ぼす影響を,感染3日後の肺から回収した幼虫数を計数して調べた.雌ラットの糞線虫に対する感受性は加齢とともに増加するエストロゲンと反対に減少を示した.6週および10週齢の雌ラットの感染感受性は3週齢と比較しそれぞれ9分の1および20分の1と低かった.対照的に,雄ラットの感受性は最若齢のグループで最も低く,加齢とともに増加するテストステロンに呼応するように上昇した.感受性の性差は最若齢のグループ間では見られなかったが,加齢とともに著明に認められた.}, pages = {519--521}, title = {Age- and sex-related changes in susceptibility of wistar rats to Strongyloides venezuelensis infection}, volume = {64}, year = {2002}, yomi = {井上, 陽 and イノウエ, ヨウ and ムラカミ, ノボル and ホリイ, ヨウイチロウ and 井上, 陽 and イノウエ, ヨウ} }