@article{oai:miyazaki-u.repo.nii.ac.jp:00000356, author = {内田, 和幸 and Uchida, Kazuyuki and 村中, 美樹 and Muranaka, Miki and 堀井, 洋一郎 and Horii, Yoichirou and 村上, 昇 and Murakami, Noboru and Yamaguchi, Ryoji and 山口, 良二 and 立山, 晉 and Tateyama, Susumu and 村中, 美樹 and Muranaka, Miki}, issue = {2}, journal = {The journal of veterinary medical science}, month = {Feb}, note = {On March 22, 1998, a mature, male, hyposthenic Pacific striped dolphin (Lagenorhynchus obliquidens) was stranded at Aoshima Beach in Miyazaki prefecture, Japan. A necropsy performed 14 hr after death revealed mild diffuse congestion and edema of the leptomeninges and mild pulmonary atelectasis. Histopathologically, non-purulent inflammatory were observed throughout the cerebrum, thalamus, midbrain, pons, medulla oblongata, and spinal cord. Hematoxylin and eosin stain revealed no viral inclusion bodies. Immunohistochemistry using a monoclonal antibody against nucleoprotein of canine distemper virus (CDV-NP) revealed a number of CDV-NP-positive granular deposits in the cytoplasm and cell processes of the degenerating or intact neurons. The present paper is a first report of spontaneously occurred morbillivirus infection in a dolphin at the Pacific Ocean around Japan., 1998年3月22日に宮崎県青島海岸に重度の衰弱状態のカマイルカLagenorhynchus obliquidensが漂着した. 死亡14時間後の剖検では, 軽度の肺虚脱, 脳イヌジステンパーウイルスの核蛋白に対するモノクローナル抗体を用いた免疫染色により, 病変部の神経細胞内に, 顆粒状のウイルス抗原が確認された. 本例は, 日本周辺域太平洋のイルカにおける初めての髄膜の軽度のび漫性うっ血および浮腫が認められた. 病理組織学的検索で非化膿性炎症が大脳, 視床脳, 中脳, 延髄, 橋, 脊髄に認められた. HE染色では, ウイルス性封入体の確認は困難であった. モルビリウイルス感染症報告例である.}, pages = {159--162}, title = {Non-Purulent Meningoencephalomyelitis of a Pacific Striped Dolphin (Lagenorhynchus obliquidens). The First Evidence of Morbillivirus Infection in a Dolphin at the Pacific Ocean around Japan}, volume = {61}, year = {1999}, yomi = {ウチダ, カズユキ and ムラナカ, ミキ and ホリイ, ヨウイチロウ and ムラカミ, ノボル and ヤマグチ, リョウジ and タテヤマ, ススム and ムラナカ, ミキ} }