@article{oai:miyazaki-u.repo.nii.ac.jp:00003370,
 author = {北原, 豪 and Kitahara, Go and 邉見, 広一郎 and Henmi, Koichiro and 鈴木, 義人 and Suzuki, Yoshihito and 日高, 亨介 and Hidaka, Kyosuke and 中間, 由規 and 笹倉, 春美 and Sasakura, Harumi and 峯, 雄太 and Mine, Yuta and 篠原, 萌 and Shinohara, Moe and 白尾, 優佳 and Shirao, Yuka and Kobayashi, Ikuo and 小林, 郁雄 and 上村, 俊一 and Kamimura, Shunichi and Henmi, Kouichiro and 鈴木, 義人 and Suzuki, Yoshihito and 日高, 亨介 and Hidaka, Kyosuke and Nakama, Yoshiki and 笹倉, 春美 and Sasakura, Harumi and 峯, 雄太 and Mine, Yuta and 白尾, 優佳 and Shirao, Yuka and 上村, 俊一 and Kamimura, Shunichi},
 journal = {宮崎大学農学部研究報告, Bulletin of the Faculty of Agriculture University of Miyazaki},
 month = {Feb},
 note = {Effect of progesterone-releasing intra vaginal device (PRID) with estrogen (E2) capsule on postpartum uterine involution and conception rate with timed artificial insemination (TAl) were investigated in Japanese Black Cows. On the day when GnRH-B (GnRH-Buserelin) or PGF2α (Prostaglandin F2α) analog was administered on Day 0 (30 days after parturition), the ratio of cows possessing functional corpus luteum (CL) and plasma progesterone concentrations on Day 7 were significantly increased (P < 0.01) as compared on Day O. From Day 7 to Day 16, PRID was inserted into the vagina of cows. At the time of the PRID removal, PGF2α analog was administered, and E2 at 24 h or GnRH-F (GnRH-Fertirelin) at 48 h after PRID removal was treated, and TAl was performed at 56 h after PRID removal. The conception rate by TAl was increased in the cows that possessing functional CL compared in the cows without CL on Day 7. Also, the uterus significantly involuted with their diameter from 40.5 ± 6.2 mm on Day 0 to 33.4 ± 3.2 mm on Day 28 (P < 0.01), and the viable bacterial count in the external uterine orifice (CFU) showed a tendency to decrease from 2.6 ± 3.5 CFU on Day 0 to 1.0 ± 1.2 CFU on Day 28 (P = 0.63). In conclusion, the activation of folliculogenesis with PRID insertion in early postpartum have promoted the uterine involution, and contributed the increase of the conception rate by TAl., 黒毛和種牛において, 分娩後の子宮修復や定時人工授精(定時AI) に対するエストロジェン(E2)カプセルのついたプロジェステロン(P4)徐放剤(PRID)の効果を調べた. その結果, Day 0(分娩後30日)にGnRH-B(酢酸ブセレリン10μg) か, PGF2α(クロプロステノール500μg)を投与すると, Day 7で卵巣に機能的な黄体のある牛が増加し, 血中P4濃度もDay 0 と比較し有意に上昇した(P<0.01). 今回, Day 7からDay 16まで腟内にPRIDを挿入, 抜去時にPGF2αを投与, その後24時間に安息香酸エストラジオール1mgまたは48時間にGnRH-F(酢酸フェルチレリン100μg)を筋肉内投与して, 56時間に定時AIを行った. その結果, 定時AIの受胎率はDay 7に黄体がない牛よりもある牛で高い傾向にあった. また, Day 0からDay 8にかけ, 左右子宮角の長さは有意に短くなり(P<0.01), 同時に外子宮口の細菌数も減少する傾向にあった. 結論として, 分娩後早期からの卵巣賦活とPRID処置は, 子宮修復を促し, 受胎率の向上に寄与することが示された.},
 pages = {169--173},
 title = {分娩後早期のプロジェステロン徐放剤PRIDの腟内挿入が黒毛和種牛の子宮修復と受胎率に及ぼす影響},
 volume = {56},
 year = {2010},
 yomi = {キタハラ, ゴウ and ヘンミ, コウイチロウ and スズキ, ヨシヒト and ヒダカ, キョウスケ and ササクラ, ハルミ and ミネ, ユウタ and シノハラ, モエ and シラオ, ユカ and コバヤシ, イクオ and カミムラ, シュンイチ and スズキ, ヨシヒト and ヒダカ, キョウスケ and ササクラ, ハルミ and ミネ, ユウタ and シラオ, ユカ and カミムラ, シュンイチ}
}