@article{oai:miyazaki-u.repo.nii.ac.jp:00003287, author = {浜名, 克己 and Hamana, Katsumi and 大塚, 宏光 and Otsuka, Hiromitsu and 黒田, 治門 and Kuroda, Haruto and 芦沢, 広三 and Ashizawa, Hirozo and 野坂, 大 and Nosaka, Dai and 斎藤, 勇夫 and Saito, Isao and 新城, 敏晴 and Shinjo, Toshiharu and 村上, 隆之 and Murakami, Takayuki and 新城, 敏晴 and Shinjo, Toshiharu}, issue = {1}, journal = {宮崎大学農学部研究報告, Bulletin of the Faculty of Agriculture, Miyazaki University}, month = {Oct}, note = {1. 生後約100日令の豚を1区10頭ずつ4区に分け, それぞれ微粉(粒径1mm), ペレット(微粉のペレット),粗粉(3.5mm)およびα化穀類を給与飼料として83日間の飼養試験を実施した.15日ごとに臨床観察,体重測定,血液・胃液・糞便検査を実施し,最後にと殺解体して胃病変の観察を行なった. 2. 増体量はペレット区が最もよく,ついでα化穀類区であり,微粉区と粗粉区の差はあまりなかった,技肉歩留りもこの順となった. 3. 前胃部病変はペレット区と微粉区はいずれも100%の発生率を示し, とくにペレット区は潰瘍や糜爛を含む重度変化が主であり,かつ3例に剥離が認められた. 粗粉区の発生率も80%と高いが,軽症例がほとんどで3例に重度角化が認められた. α化穀類区はわずか10%の発生率でこの1例も初期角化であった. いずれも生前に胃潰瘍を思わせる所見はまったくなかったので臨床的には潜在性胃潰瘍であったといえる. 4. 飼料の粒状性が胃病変の発生に重要な役割りを果していることが確認されたが,本試検ではさらに豚の保定によるストレスや暑熱時の影響も関与したと考えられる. 5. RBC, Hb, Ht, MCV, MCH, MCHC, WBC, 白血球百分率,黄疸指数, p-TP, S-TP, 血清蛋白分画, A/G比を15日おきに測定した結果, いずれの項目も各試験区間における有意差は認められなかった. 6. 血清蛋白分画うち α-, β-, γ-Globulinはいずれも各区における差はなく,試験第45日(生後143日)まで増加して平衡に達したが,これは発育に伴なう変化である. 7. 試験第75日目の血清についてBUN, Glucose, Cholesterol, Bilirubin, ALP, GOT, GPT, LDH を測定したが各区間の差は認められなかった. 8. 胃液および糞便の潜血反応の結果はまちまちで,診断の助けとならないことがわかった., Forty weanling pigs were separated in four groups according to the feeding program which were fine cracked corns (1 mm. screen), pelleted corns made from fine cracked corns, coarse cracked corns (3.5 mm. screen) and gelatinized nonground corns. During the experimental periods of 83 days, clinical observations, body weight record, blood, gastric juice and fecal analysis were performed every 15 days. Pigs were slaughtered on the last day of experiment and gastric lesions were examined pathologically. Body weight increased most rapidly in the group fed pelleted corns and the group fed gelatinized corns followed it. No significant differences were found between the groups fed fine and coarse cracked corns. The percentage of carcass to body weight were also in this order. Hundred percent of the groups fed pelleted corns and fine cracked corns had mucosal lesions in the esophagogastric regions. Especially in the pellets feeding produced more heavy lesions including ulceration, erosion, severe cornification and desquamation. Eighty percent of the group fed coarse cracked corns developed mucosal lesions, but most of them belonged to mild cornification. Only 10 percent (1 case) of the group fed gelatinized corns produced mucosal lesions and it was mild cornification. These lesions were observed only after slaughter. Therefore, they all belong to the subclinical form of the gastric ulcers of swine. It was confirmed that particle size of corns markedly affected the development of gastric lesions. In this experiment, the stress including periodical blood sampling from anterior vena cava, gastric juice sampling by oral catheterization and hot weather were also considered to be contributing factors. Every 15 days during the experiment, blood were analyzed in erythrocyte count, hemoglobin level, packed cell volume, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, leukocyte count, differential count of leukocyte, icteric index, plasma and serum total protein concentration, relative and absolute concentration of serum protein components and albumin-globulin ratio. However, no significant differences were found in all the items examined between the groups. In all groups, α-, β- and γ-globulin continued to increase and reached to the constant levels on the 45th day of experiment which coincided approximately 143 days of age. These changes were considered to be an animal's adaptation to growth. On the 75th day of experiment, blood serum were analyzed in blood urea nitrogen, glucose, cholesterol, bilirubin, alkaline phosphatase, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase and lactic dehydrogenase. However, they had no significant differences between the groups either. Occult blood examination of gastric juice and feces showed various results and had no diagnostic value.}, pages = {231--241}, title = {豚の胃潰瘍に関する研究(第5報) : 第2次飼養試験 : 臨床所見と血液諸性状の変化}, volume = {22}, year = {1975}, yomi = {シンジョウ, トシハル and シンジョウ, トシハル} }