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New Models of Epilepsy
http://hdl.handle.net/10458/2117
http://hdl.handle.net/10458/211788e9e5b5-3543-4157-84d4-9fb47bab527a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
4-7a_ueda1998-nrc_newsletter_v05_n01.pdf (189.2 kB)
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| Item type | 一般雑誌記事 / Article(1) | |||||
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| 公開日 | 2009-07-30 | |||||
| タイトル | ||||||
| タイトル | New Models of Epilepsy | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| 著者 |
Ueda, Yuto
× Ueda, Yuto× Willmore, L. James |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Clinical treatment of epilepsy and the knowledge gained from observing patients suggest the parallel efforts necessary to understand basic mechanisms of epilepsy in the laboratory. Behavior of patients during seizures of temporal lobe origin, coupled with the histopathological patterns in hippocampal structures have motivated use of the amygdala and hippocampus to create models of epilepsy. Older animal models have been developed with methods that use injection of metallic cobalt or alumina gel, or with methods that deliver convulsant chemicals or electrical stimuli into brain regions. Although recent work with rodents that have genetically determined seizures holds hope for more detailed understanding of the molecular mechanisms of epilepsy, the use of animal models with induced seizures is still the most commen vehicle for study. In light of their usefulness in seizure research, two procedures are worth discussion: kindling and the study of interictal events, and ferric chloride injections. | |||||
| 言語 | en | |||||
| 書誌情報 |
en : NRC NEWSLETTER 巻 5, 号 1, p. 1,4-6, 発行日 1998 |
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| 出版者 | ||||||
| 出版者 | The University of Texas-Houston Health Science Center | |||||
| 言語 | en | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
