{"created":"2023-05-15T09:56:39.954163+00:00","id":301,"links":{},"metadata":{"_buckets":{"deposit":"d040fe86-6aa6-4487-a347-fe63a3a62e77"},"_deposit":{"created_by":5,"id":"301","owner":"5","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"301"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00000301","sets":["74","74:26"]},"author_link":["1417","16713","1419","2693","2692"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"1061","bibliographicPageStart":"1057","bibliographicVolumeNumber":"72","bibliographic_titles":[{"bibliographic_title":"The journal of veterinary medical science","bibliographic_titleLang":"en"},{"bibliographic_title":"J. vet. med. sci","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In vivo Simian Immunodeficiency Virus （SIV） challenge of macaques demonstrated the earlier disappearance of CD4 and CD8 double-positive （DP） T cells than CD4 single-positive T cells, although its mechanism remains unclear. Here we found that peripheral DP T cells were readily induced to express CCR5, a secondary receptor for SIV, by in vitro stimulation with either concanavalin A or anti-CD3/CD28 monoclonal antibodies. Activated DP T cells were more vulnerable to SIV infection, indicating that the ability of DP T cells to readily express CCR5 after activation may hasten DP T cell death by SIV infection in vivo.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Japanese Society of Veterinary Science","subitem_publisher_language":"en"},{"subitem_publisher":"日本獣医学会","subitem_publisher_language":"ja"}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"20224239","subitem_relation_type_select":"PMID"}}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10796138","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09167250","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Matsumoto, Yusuke","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1417","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Miura, Tomoyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16713","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Akari, Hirofumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1419","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Goto, Yoshitaka","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2693","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Haga, Takeshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2692","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"displaytype":"detail","filename":"3246haga.pdf","filesize":[{"value":"382.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"3246haga.pdf","url":"https://miyazaki-u.repo.nii.ac.jp/record/301/files/3246haga.pdf"},"version_id":"525ba9ce-b046-46f6-887f-076f244a6694"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"CCR5, CD4 and CD8 double-positive T cells, Simian Immunodeficiency Virus","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Peripheral Blood CD4 and CD8 Double-Positive T Cells of Rhesus Macaques Become Vulnerable to Simian Immunodeficiency Virus by in Vitro Stimulation Due to the Induction of CCR5","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Peripheral Blood CD4 and CD8 Double-Positive T Cells of Rhesus Macaques Become Vulnerable to Simian Immunodeficiency Virus by in Vitro Stimulation Due to the Induction of CCR5","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"5","path":["74","26"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-05-18"},"publish_date":"2011-05-18","publish_status":"0","recid":"301","relation_version_is_last":true,"title":["Peripheral Blood CD4 and CD8 Double-Positive T Cells of Rhesus Macaques Become Vulnerable to Simian Immunodeficiency Virus by in Vitro Stimulation Due to the Induction of CCR5"],"weko_creator_id":"5","weko_shared_id":2},"updated":"2023-07-29T22:42:16.096775+00:00"}