@article{oai:miyazaki-u.repo.nii.ac.jp:00000289, author = {内田, 和幸 and Uchida, Kazuyuki and 作美, 礼乃 and Yamaguchi, Ryoji and 山口, 良二 and 立山, 晉 and Tateyama, Susumu and 小川, 博之 and 大塚, 宏光 and Otsuka, Hiromitsu and Mina, Rostami B. and Mina, Rostami and Sakumi, Ayano and Ogawa, Hiroyuki and Mina, Rostami B. and Mina, Rostami}, issue = {6}, journal = {The journal of veterinary medical science}, month = {Dec}, note = {A mammary mass approximately 60 cm in diameter, which developed in the left udddr of a 17-month-old Holstein cow, was removed surgically. The mass was well demarcated from the surrounding tissues and its cut surface was lobular in appearance. Microscopically, the mass consistcd of a proliferation of well differentiated ducts and mucinous connective tissue. Immunohistochemically, the proliferative stroma contained two distinct cell types; vimentin-positive fibroblasts and spindle cells positive for vimentin and actin at the periphery of the ducts. The biological features of the present mammary tumor are thought to be generally compatible with those of mammary tibroadenoma reported in humans and dogs., 17ヵ月齢のホルスタイン牛の左側乳房に発生した直径60cmの腫瘤を外科的に摘出した. この腫瘤は周囲組織との境界が明瞭で, 割面は小葉構造を示していた. 組織学的には, 本腫瘤は導管と粘液に富む間質の増殖により構成されていた. 免疫組織化学的には, 間質にビメンチン陽性の線維芽細胞と, アクチン・ビメンチンともに陽性の筋線維芽細胞が増殖していた. 以上の本腫瘍の特徴は, ヒ卜およびイヌの乳腺線維腺腫に類似していた.}, pages = {1171--1172}, title = {Mammary Fibroadenoma in a Young Holstein Cow}, volume = {56}, year = {1994}, yomi = {ウチダ, カズユキ and サクミ, アヤノ and ヤマグチ, リョウジ and タテヤマ, ススム and オガワ, ヒロユキ and オオツカ, ヒロミツ} }