@article{oai:miyazaki-u.repo.nii.ac.jp:00000280,
 author = {熊元, 一徳 and Kumamoto, Kazunori and 内田, 和幸 and Uchida, Kazuyuki and Yamaguchi, Ryoji and 山口, 良二 and 溝辺, 牧男 and 奈須, 久岳 and 立山, 晉 and Tateyama, Susumu and 熊元, 一徳 and Kumamoto, Kazunori and Mizobe, Makio and Nasu, Hisataka},
 issue = {5},
 journal = {The journal of veterinary medical science},
 month = {May},
 note = {A malignant aortic body tumor was observed in a 5-year-old female Holstein cow. The neoplastic mass, of 22×17×15 cm in size, was located at the base of the left atrium, having irregular lobular structures. The tumor cells had slightly eosinophilic cytoplasm, and a round or oval nucleus. Metastasid was only present in the premediastinal lymph node. The tumor cells exhibited intense immunoreactivity for neuron-specific enolase （NSE） and synaptophysin, and were moderately positive for chromogranin A. Electron-microscopy revealed membrane-limited granules in the cytoplasm. The cultured cells were spindle in shape, and having projectional cytoplasm. They were intensely positive for NSE, synaptophysin, chromogranin A, and neurofilament （200 kD）. Consequently, this case was diagnosed as a malignant aortic body tumor from the neuroecrodermal origin., 雌ホルスタイン種牛の心房大動脈基始部に, 22×17×15 cm大の灰白色腫瘤を認めた. 組織学的には, 円形から卵円形の核とエオジン淡染の細胞質を有する腫瘍細胞が, 充実性に増殖し, 毛細血管を伴って, 結合組織で巣状に区画されていた. 縦隔リンパ節に転移を認めた. NSE, シナプトフィジン, クロモグラニンAに陽性で, 培養細胞ではNFにも陽性を示した. 電子顕微鏡による観察では細胞質内に限界膜の明瞭な顆粒を認め, 本症例を悪性大動脈小体腫瘍と診断した.},
 pages = {383--385},
 title = {Malignant Aortic Body Tumor in a Holstein Cow},
 volume = {59},
 year = {1997},
 yomi = {クマモト, カズノリ and ウチダ, カズユキ and ヤマグチ, リョウジ and ミゾベ, マキオ and ナス, ヒサタカ and タテヤマ, ススム and クマモト, カズノリ}
}