@article{oai:miyazaki-u.repo.nii.ac.jp:00000278, author = {超, 徳明 and Yamaguchi, Ryoji and 山口, 良二 and 立山, 晉 and Tateyama, Susumu and 小川, 博之 and 山崎, ゆみ and Yamazaki, Yumi and Zhao, Deming and Ogawa, Hiroyuki and 山崎, ゆみ and Yamazaki, Yumi}, issue = {4}, journal = {The journal of veterinary medical science}, month = {Aug}, note = {Disseminated hemangiosarcoma was encountered in a 12-year-old female Maltese dog. Tumor tissues were dispersed on the serosal surface of the liver, kidney, digestive tract, omentum and diaphragm. Metastatic lesions were not observed in the parenchyma of the lung and heart. The spleen was enlarged with rupture at the anterior region of the hilus. The disseminated protruding tumor masses could be easily peeled off from the organ surfaces. The tumor cells were round or spindle in shape, with hyperchromatic nuclei containing prominent nucleoli. Various-sized vascular spaces containing erythrocytes and serum could be identified in this tumor. This case was diagnosed as hemangiosarcoma originating from the spleen with abdominal dissemination., 12歳, 雌のマルチーズ犬の腹腔内に播種性転移を示した脾臓原発血管肉腫を認めた. 脾臓は著しく腫大し, 脾頭部は破裂していた. 肝臓, 腎臓, 消化管, 大網及び横隔膜の漿膜面に, 大小不同の転移性腫瘍結節が認められた. これらの結節は漿膜面から隆起し,周囲は線維組織で囲まれていたが, 容易に剥離出来た. 各臓器の実質には腫瘍病変は認められなかった. 腫瘍細胞は円形または紡錘形を呈し, その核はクロマチンに富み, 核小体は明瞭であった. 胸腔内臓器や他の組織には著変は認められなかった.}, pages = {753--755}, title = {Canine Splenic Hemangiosarcoma with Abdominal Dissemination}, volume = {56}, year = {1994}, yomi = {ヤマグチ, リョウジ and タテヤマ, ススム and オガワ, ヒロユキ and ヤマザキ, ユミ and ヤマザキ, ユミ} }