{"created":"2023-05-15T11:20:23.448225+00:00","links":{},"metadata":{"_buckets":{"deposit":"06f9ea5a-38f4-4f3f-b715-5d1f12b326f4"},"_deposit":{"id":"266.1","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"266.1"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00000266.1","sets":["74:26"]},"author_link":["1071","1072","1073","1074","1075","1076","1077","1078","1079"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-05-22","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-3","bibliographicPageEnd":"112","bibliographicPageStart":"108","bibliographicVolumeNumber":"543","bibliographic_titles":[{"bibliographic_title":"FEBS letters : for the rapid publication of short reports in biochemistry, biophysics and molecular biology","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Palytoxin （PTX） induces a cation channel through interaction\nwith Na+,K+-ATPase. It is unclear how this action relates to the enzyme\ncatalytic activity. We examined whether the action of PTX depends on\nthe catalytic domain specific for Na+,K+-ATPase. Wild-type\nNa+,K+-ATPase α-subunit （NNN） or its chimera （NCN）, in which the\ncatalytic domain was replaced with that of SERCA, was co-expressed with\nβ-subunit in the yeast Saccharomyces cerevisiae. PTX （0.1-100 nM）\nincreased K+ efflux in NNN- or NCN-transfected cells to a similar degree\nbut not in non-transfected cells. When ouabain-resistant NNN and NCN\nwere expressed, PTX also increased K+ efflux. Ouabain inhibited the\neffect of PTX in NNN- or NCN-cells but not in ouabain-resistant cells.\nThese data suggest that the channel-forming action of PTX does not depend\non the catalytic domain species.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"<a href=\"http://www.febsletters.com/\" target=\"_blank\">Journal HP</a>","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00642943","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00145793","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"伊藤, 勝昭","creatorNameLang":"ja"},{"creatorName":"イトウ, カツアキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ito, Katsuaki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Toyoda, Isao","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Higashiyama, Masato","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uemura, Daisuke","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Masa H.","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshimura, Shige H.","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishii, Toshiaki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeyasu, Kunio","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"displaytype":"detail","filename":"FEBS543_108_2003.pdf","filesize":[{"value":"117.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"FEBS543_108_2003.pdf","url":"https://miyazaki-u.repo.nii.ac.jp/record/266.1/files/FEBS543_108_2003.pdf"},"version_id":"240e3e66-cf19-4202-b6cb-502e102109a0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Palytoxin, Na+,K+-ATPase, Channel, Catalytic domain, Yeast, Chimera","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"2","path":["26"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-01-30"},"publish_date":"2008-01-30","publish_status":"0","recid":"266.1","relation_version_is_last":true,"title":["Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2023-07-21T09:29:20.900919+00:00"}