| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2026-03-23 |
| タイトル |
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|
タイトル |
TiO2 Photocatalyst Inactivates Highly Pathogenic Avian Influenza Virus and H1N1 Seasonal Influenza Virus via Multi-Antiviral Effects |
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言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
キーワード |
aerosol |
| キーワード |
|
|
言語 |
en |
|
キーワード |
H1N1 influenza virus |
| キーワード |
|
|
言語 |
en |
|
キーワード |
highly pathogenic avian influenza virus |
| キーワード |
|
|
言語 |
en |
|
キーワード |
inactivation |
| キーワード |
|
|
言語 |
en |
|
キーワード |
liquid |
| キーワード |
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|
言語 |
en |
|
キーワード |
TiO2 photocatalyst |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
| 著者 |
Matsuura, Ryosuke
齊藤, 暁
WEKO
33890
e-Rad_Researcher
30621792
| ja |
齊藤, 暁
宮崎大学
|
| ja-Kana |
サイトウ, アカツキ
|
| en |
Saito, Akatsuki
University of Miyazaki
|
Search repository
Nagata, Fumihiro
Fukushi, Noriko
Matsumoto, Yasunobu
Fukushima, Takashi
Fujimoto, Kazuhiro
Kozaki, Masato
Somei, Junichi
Aida, Yoko
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
The highly pathogenic avian influenza virus (HPAIV) is widely distributed worldwide and causes significant economic losses. Transmission of HPAIV occurs through direct contact between infected and susceptible birds or indirectly via contaminated materials. In recent years, airborne transmission of HPAIV has also been reported, underscoring the need for novel approaches to effectively inactivate airborne HPAIV. Photocatalysts have attracted significant attention as potential antiviral agents. In this study, we demonstrated that a TiO<inf>2</inf>-mediated photocatalytic reaction inactivated HPAIV and H1N1 seasonal influenza viruses in liquid, reducing their infectivity by 90.7% and 94.4%, respectively, after 60 min. Mechanistic analyses revealed decreased virion size and surface structure disruption, as determined by transmission electron microscopy. Additional evidence of viral protein and genome damage was obtained using Western blotting and RT-qPCR, respectively. Given the broad antiviral activity of photocatalysts, these findings suggest that they can inactivate influenza viruses regardless of strain or subtype. Notably, photocatalysts inactivated 80% of aerosolized H1N1 seasonal influenza viruses within 5 min. These results provide strong evidence that photocatalysts are capable of inactivating airborne influenza viruses. This study represents the first demonstration that photocatalysts can inactivate HPAIV and aerosolized influenza viruses. These findings provide strong evidence that photocatalysts represent a promising countermeasure against HPAIV, with potential applicability across different strains and subtypes. |
|
言語 |
en |
| 書誌情報 |
en : Catalysts
巻 16,
号 2,
p. 168,
発行日 2026-02-04
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| 出版者 |
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出版者 |
MDPI AG |
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言語 |
en |
| ISSN |
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|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
20734344 |
| DOI |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.3390/catal16020168 |
| 権利 |
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|
権利情報 |
© 2026 by the authors. |
|
言語 |
en |
| 著者版フラグ |
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出版タイプ |
VoR |
Fulltext (1.8 MB)
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