| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2026-02-03 |
| タイトル |
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タイトル |
Current Practice and Safety of Invasive Coronary Function Testing: A Nationwide Multicenter Survey in Japan |
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言語 |
en |
| 言語 |
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言語 |
eng |
| キーワード |
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言語 |
en |
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キーワード |
coronary flow reserve |
| キーワード |
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言語 |
en |
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キーワード |
coronary microvascular dysfunction |
| キーワード |
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言語 |
en |
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キーワード |
coronary spasm |
| キーワード |
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言語 |
en |
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キーワード |
the index microcirculatory resistance |
| キーワード |
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言語 |
en |
|
キーワード |
vasospastic angina |
| 資源タイプ |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
open access |
| 著者 |
Nishi, Takeshi
中井, 陸運
WEKO
35309
e-Rad_Researcher
50595147
| ja |
中井, 陸運
宮崎大学
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| ja-Kana |
ナカイ, ミチカズ
|
| en |
Nakai, Michikazu
University of Miyazaki
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Search repository
Ishii, Masanobu
Matoba, Tetsuya
Muramatsu, Takashi
Tsujita, Kenichi
Kozuma, Ken
Kobayashi, Yoshio
Uemura, Shiro
海北, 幸一
WEKO
34072
e-Rad_Researcher
30346978
| ja |
海北, 幸一
宮崎大学
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| ja-Kana |
カイキタ, コウイチ
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| en |
Kaikita, Koichi
University of Miyazaki
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Search repository
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background: Coronary vasomotor dysfunction—including vasospastic angina and coronary microvascular dysfunction—is a key mechanism underlying ischemia or myocardial infarction with nonobstructive coronary arteries (INOCA/MINOCA). While invasive coronary function testing (CFT) provides important diagnostic insights, its real-world use and safety—especially in emergency settings—remain poorly defined. Objectives: The purpose of this study was to assess the current practice, diagnostic yield, and safety of CFT, including acetylcholine (ACh) and ergonovine (ERG) provocation tests and coronary microvascular assessments using coronary flow reserve (CFR) and index of microcirculatory resistance (IMR), in Japan. Methods: We conducted a nationwide cross-sectional survey of 235 institutions affiliated with the Japanese Cardiovascular Intervention and Therapeutics Society. Data on procedure volume, positivity rates, and complications were collected for tests performed between January 2022 and December 2023. Results: Among 6,983 provocation tests, 4,700 were ACh (4,327 elective and 373 emergency) and 2,283 were ERG (2,009 elective and 274 emergency). CFR/IMR was measured in 2,192 cases. Positivity rates were 50.9% for ACh and 32.5% for ERG. Major complications occurred in 1.4% of ACh and 0.4% of ERG tests, with no significant difference between emergency and elective settings. Abnormal CFR/IMR findings were more common in emergency cases (45.9% vs 34.8%; P < 0.001), while complications remained rare (0.05%). Conclusions: This large-scale survey confirms the feasibility and safety of invasive CFT, even in emergency settings. These findings support its broader adoption in the diagnostic workup of INOCA and MINOCA. |
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言語 |
en |
| 書誌情報 |
en : Jacc Advances
巻 5,
号 1,
p. 102475,
発行日 2026-01
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| 出版者 |
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出版者 |
Elsevier BV |
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言語 |
en |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
2772963X |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
2772-963X |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1016/j.jacadv.2025.102475 |
| 権利 |
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|
権利情報 |
© 2026 The Authors. |
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言語 |
en |
| 著者版フラグ |
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出版タイプ |
VoR |
Fulltext (1.9 MB)
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