| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2026-01-19 |
| タイトル |
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タイトル |
Nationwide Analysis of Spontaneous Coronary Artery Dissection-Related Acute Myocardial Infarction in Japanese Patients Aged ≤60 Years Using the Administrative JROAD-DPC Database |
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言語 |
en |
| 言語 |
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言語 |
eng |
| キーワード |
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言語 |
en |
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キーワード |
Acute myocardial infarction |
| キーワード |
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言語 |
en |
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キーワード |
All-cause mortality |
| キーワード |
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言語 |
en |
|
キーワード |
Diagnosis procedure combination |
| キーワード |
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言語 |
en |
|
キーワード |
Spontaneous coronary artery dissection |
| 資源タイプ |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
open access |
| 著者 |
Wayama, Keima
| en |
Wayama, Keima（Personal）
National Cerebral and Cardiovascular Center
|
Search repository
Kataoka, Yu
| en |
Kataoka, Yu（Personal）
National Cerebral and Cardiovascular Center
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Search repository
Kanaoka, Koshiro
| en |
Kanaoka, Koshiro（Personal）
National Cerebral and Cardiovascular Center
|
Search repository
中井, 陸運
WEKO
35309
e-Rad_Researcher
50595147
| ja |
中井, 陸運
宮崎大学
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| ja-Kana |
ナカイ, ミチカズ
|
| en |
Nakai, Michikazu
University of Miyazaki
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Search repository
Iwanaga, Yoshitaka
| en |
Iwanaga, Yoshitaka（Personal）
National Cerebral and Cardiovascular Center
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Search repository
Sumita, Yoko
| en |
Sumita, Yoko（Personal）
National Cerebral and Cardiovascular Center
|
Search repository
Miyamoto, Yoshihiro
| en |
Miyamoto, Yoshihiro（Personal）
National Cerebral and Cardiovascular Center
|
Search repository
Yasuda, Satoshi
Noguchi, Teruo
| en |
Noguchi, Teruo（Personal）
National Cerebral and Cardiovascular Center
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Search repository
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Background: Spontaneous coronary artery dissection (SCAD) causes acute myocardial infarction (AMI). Clinical characteristics of SCAD patients remain insufficiently understood.
Methods and Results: We analyzed AMI patients aged ≤60 years using the nationwide Japanese Registry of All Cardiac and Vascular Diseases–Diagnosis Procedure Combination database (2012.04.01–2022.03.31). SCAD was defined by International Classification of Diseases, 10th revision code I24.8 and the presence of keyword ‘coronary artery dissection’. The primary outcome was in-hospital all-cause mortality. Among 96,304 eligible patients, 330 (0.34%) had SCAD. SCAD patients were younger (P<0.001), more often female (P<0.001), and had fewer atherogenic risk factors. They less frequently received aspirin (P<0.001), angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker (P<0.001), statins (P<0.001), and percutaneous coronary intervention (PCI; P<0.001). After propensity score matching, in-hospital all-cause mortality did not differ between SCAD and non-SCAD patients (1.0% vs. 2.9%; P=0.142). The subgroup analysis revealed that the use of aspirin was associated with a lower adjusted in-hospital all-cause mortality (P=0.002), whereas primary PCI (P=0.223), β-blocker (P=0.646), and statin (P=0.608) were not. Of note, older SCAD patients were more likely to exhibit inferior MI (P=0.036 for trend) with shorter duration of hospitalization (P=0.025 for trend).
Conclusions: Short-term outcomes in SCAD patients are comparable with those of atherosclerotic AMI. While aspirin lowered in-hospital mortality, PCI, β-blocker, and statin did not. Our findings suggest the need for physicians to select appropriate therapeutic management in SCAD patients to achieve better outcomes. |
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言語 |
ja |
| 書誌情報 |
en : Circulation reports
巻 7,
号 12,
p. 1249-1258,
発行日 2025-12-10
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| 出版者 |
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出版者 |
Japanese Circulation Society |
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言語 |
en |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
24340790 |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1253/circrep.CR-25-0202 |
| 権利 |
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権利情報 |
© 2025, THE JAPANESE CIRCULATION SOCIETY |
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言語 |
en |
| 著者版フラグ |
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出版タイプ |
VoR |
Fulltext (1.3 MB)
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