| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-12-26 |
| タイトル |
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タイトル |
Unplanned Hospitalization Due to All-Cause Morbidity and Its Real-World Management Practices in Patients With Fontan Circulation |
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言語 |
en |
| 言語 |
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言語 |
eng |
| キーワード |
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言語 |
en |
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キーワード |
Fontan |
| キーワード |
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言語 |
en |
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キーワード |
heart failure |
| キーワード |
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言語 |
en |
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キーワード |
hospitalization |
| キーワード |
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言語 |
en |
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キーワード |
management |
| キーワード |
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言語 |
en |
|
キーワード |
protein‐losing enteropathy |
| 資源タイプ |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
open access |
| 著者 |
Ohuchi, Hideo
| en |
Ohuchi, Hideo（Personal）
National Cerebral and Cardiovascular Center
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Search repository
Takei, Kohta
Muneuchi, Jun
| en |
Muneuchi, Jun（Personal）
Kyushu Hospital Japan Community Healthcare Organization
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Search repository
Kasahara, Shingo
Ishikawa, Yuichi
Muraji, Shota
Tsukada, Masanori
Nii, Masaki
Ono, Shin
Takamuro, Motoki
| en |
Takamuro, Motoki（Personal）
Hokkaido Medical Center for Child Health and Rehabilitation
|
Search repository
Saiki, Hirofumi
Fujino, Mitsuhiro
Kuraishi, Kenji
Lin, Lisheng
Miyazaki, Aya
Sakamoto, Ichiro
Masutani, Satoshi
Hayabuchi, Yasunobu
Ohashi, Hiroyuki
Yasuda, Kenji
Seki, Mitsuru
Mori, Aki
中井, 陸運
WEKO
35309
e-Rad_Researcher
50595147
| ja |
中井, 陸運
宮崎大学
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| ja-Kana |
ナカイ, ミチカズ
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| en |
Nakai, Michikazu
University of Miyazaki
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Search repository
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Management strategies of unplanned hospitalizations (UPH) vary and have not been well characterized in patients with Fontan circulation./We prospectively followed 3226 Fontan patients for 3 years to characterize the current UPH status and elucidate the associations between in-hospital management strategies and postdischarge outcomes./A total of 243 UPHs occurred (2.5 cases/100 person-years). Fontan-related UPHs accounted for 154 cases (63%), most commonly due to heart failure (19%), protein-losing enteropathy (16%), hemorrhage (14%), arrhythmia (9%), thromboembolism (3%), and plastic bronchitis (2%). Fontan-unrelated UPHs (89 cases; 37%) were mainly due to infections (19%). Adult patients were more frequently hospitalized for hemorrhage and thromboembolism (P<0.05). The longest length of hospital stay was observed in protein-losing enteropathy, followed by thromboembolism and heart failure. Among nonpharmacological treatments, oxygen therapy was commonly used, followed by surgical procedures and catheter-based interventions. Among pharmacological treatments, diuretics were commonly administered, followed by heparin and catecholamines. Of 240 patients discharged alive, 76 (15.4 cases/100 person-years) were readmitted. Protein-losing enteropathy was the most frequent cause of readmission, followed by heart failure and hemorrhage. In addition to conventional risk factors, in-hospital management practices, such as oxygen therapy, surgical intervention, and diuretic adjustment were associated with readmission risk (P<0.01-0.001)./We clarified real-world practices related to UPHs in Fontan patients. Specific in-hospital treatment strategies were associated with the risk of readmission. Further studies are warranted to determine the causal relationships between treatment approaches and outcomes for standardized management strategies. |
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言語 |
en |
| 書誌情報 |
en : Journal of the American Heart Association
巻 14,
号 24,
発行日 2025-12-16
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| 出版者 |
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出版者 |
Wolters Kluwer Health |
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言語 |
en |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
20479980 |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1161/JAHA.125.044374 |
| 権利 |
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権利情報 |
© 2025 The Author(s). |
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言語 |
en |
| 著者版フラグ |
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出版タイプ |
VoR |
Fulltext (3 MB)
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