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  1. 医学部
  1. 医学部
  2. 学術雑誌掲載論文  (医学部)

Subcutaneous Migration in Paragonimiasis as a Diagnostic Clue in an Unusual Presentation: A Case Report

http://hdl.handle.net/10458/0002001889
http://hdl.handle.net/10458/0002001889
a30f632e-5593-409e-a601-4405f810196f
名前 / ファイル ライセンス アクション
20250913-153404-bm0ldk.pdf fulltext (5.2 MB)
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アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2025-10-28
タイトル
タイトル Subcutaneous Migration in Paragonimiasis as a Diagnostic Clue in an Unusual Presentation: A Case Report
言語 en
言語
言語 eng
キーワード
言語 en
キーワード eosinophilia
キーワード
言語 en
キーワード migration tract
キーワード
言語 en
キーワード paragonimiasis
キーワード
言語 en
キーワード praziquantel
キーワード
言語 en
キーワード pseudochylothorax
キーワード
言語 en
キーワード subcutaneous mass
資源タイプ
資源タイプ journal article
アクセス権
アクセス権 open access
著者 Eguchi, Mako

× Eguchi, Mako

en Eguchi, Mako(Personal)
St. Mary's Hospital

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Masumoto, Keisuke

× Masumoto, Keisuke

en Masumoto, Keisuke(Personal)
St. Mary's Hospital

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小久保, 美緒

× 小久保, 美緒

WEKO 34833
e-Rad_Researcher 00910689

ja 小久保, 美緒
宮崎大学

ja-Kana コクボ, ミオ

en Kokubo-Tanaka, Mio
University of Miyazaki

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丸山, 治彦

× 丸山, 治彦

WEKO 3231
e-Rad_Researcher 90229625

ja 丸山, 治彦
宮崎大学

ja-Kana マルヤマ, ハルヒコ

en Maruyama, Haruhiko
University of Miyazaki

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Morimoto, Satoru

× Morimoto, Satoru

en Morimoto, Satoru(Personal)
Keio University

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Mizuta, Yuichi

× Mizuta, Yuichi

en Mizuta, Yuichi(Personal)
St. Mary's Hospital

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抄録
内容記述タイプ Abstract
内容記述 Paragonimiasis is a foodborne parasitic infection caused by trematodes of the genus Paragonimus, primarily P. westermani and P. miyazakii in Japan. Though once endemic, its incidence has declined significantly in recent decades. However, globalization, changes in dietary customs, and an increase in foreign-born residents have contributed to the emergence of new cases, particularly in urban settings.

We present a case of a 25-year-old man from Cambodia, living in Japan for two years as a technical intern trainee, who developed a productive cough and pleuritic chest pain. He reported consuming raw Japanese mitten crabs seven months earlier. Initially misdiagnosed with pneumonia, his symptoms persisted despite antibiotic therapy. CT imaging revealed pleural effusion, a cavitary lesion, and a linear tract consistent with worm migration. A subcutaneous abdominal mass was noted and surgically removed. Histopathological examination revealed eosinophilic infiltration and serpiginous necrosis, suggesting larval migration. Laboratory tests showed marked eosinophilia (11,011/μL), and pleural fluid analysis indicated pseudochylothorax. ELISA confirmed antibodies against P. westermani and P. miyazakii. The patient was treated with praziquantel, leading to complete clinical and radiological resolution.

This case highlights the diagnostic challenges of paragonimiasis, especially with atypical presentations. Subcutaneous lesions are rare and often mimic benign tumors or other parasitic diseases, such as sparganosis or cysticercosis. The pulmonary findings may be confused with tuberculosis or eosinophilic pneumonia. Thus, thorough dietary and travel history-taking, cultural awareness, and a multidisciplinary diagnostic approach, including imaging, histology, and serology, are essential. Diagnosis of paragonimiasis should rely on a combination of clinical presentation, radiological findings, and serological testing, as ectopic manifestations are uncommon and may not be promptly recognized. This case underscores the need for heightened clinical awareness of re-emerging parasitic diseases in increasingly multicultural societies.
言語 en
書誌情報 en : Cureus

巻 17, 号 8, p. e90032, 発行日 2025-08-13
出版者
出版者 Springer Science and Business Media LLC
言語 en
ISSN
収録物識別子タイプ PISSN
収録物識別子 21688184
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.7759/cureus.90032
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出版タイプ VoR
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