| 著者 |
Sasaki, Fumisato
Mizukami, Kazuhiro
Akashi, Taro
Yamaguchi, Naoyuki
Gushima, Ryosuke
Miyamoto, Hideaki
Uehara, Shohei
Ono, Yoichiro
Hisabe, Takashi
Kinjo, Yuzuru
Nasu, Yuichiro
Fukuda, Kensuke
Inada, Taisuke
Sumida, Yorinobu
Akutagawa, Takashi
三池, 忠
WEKO
9206
e-Rad_Researcher
10468043
| ja |
三池, 忠
宮崎大学
|
| ja-Kana |
ミイケ, タダシ
|
| en |
Miike, Tadashi
University of Miyazaki
|
Search repository
鈴木, 翔
Fukuya, Hiroki
| en |
Fukuya, Hiroki（Personal）
National Hospital Organization Kyushu Medical Center
|
Search repository
Mukasa, Michita
Esaki, Mitsuru
Kumei, Shinsuke
| en |
Kumei, Shinsuke（Personal）
Third Department of Internal Medicine School of Medicine University of Occupational and Environmental Health Fukuoka Japan.
|
Search repository
Minoda, Yosuke
Kinjo, Tetsu
Yamaguchi, Daisuke
| en |
Yamaguchi, Daisuke（Personal）
National Hospital Organization Ureshino Medical Center
|
Search repository
Fukuda, Yoshio
Hashiguchi, Kazutoshi
Yano, Hiroki
Fujita, Hiroshi
Shimoda, Ryo
|
|
内容記述 |
Objectives
Most esophageal cancers in Japan are squamous cell carcinomas; however, there has been some concern regarding a recent increase in Barrett's esophageal adenocarcinoma (BEA). This study aimed to clarify the clinical characteristics and outcomes of patients treated via endoscopic submucosal dissection (ESD) in Kyushu, including changes over time.
Methods
This multicenter, retrospective, observational study was conducted among 21 institutes situated in Kyushu. Data from patients who underwent ESD for BEA or esophageal squamous cell carcinoma between January 2010 and December 2023 were extracted from the pathology database and reviewed.
Results
The total number of esophageal ESD cases increased from 2299 over the first 7 years to 4009 over the second seven. The incidence of BEA increased from 3.6% (86/2299) over the earlier period to 4.7% (197/4009; p = 0.034) over the latter. We analyzed data from 283 patients (287 lesions). Smaller tumor-sized lesions were detected over the latter period (14.2 ± 11.6 vs. 11.2 ± 9.5 cm2, p = 0.022), significantly reducing treatment times (122.1 ± 81.2 vs. 93.2 ± 53.3 min p < 0.001). The procedure was safe, with low incidence rates, over both the earlier and later periods (respectively), of perforation (0% vs. 1.0%), delayed bleeding (1.2% vs. 2.0%), and pneumonia (4.7% vs. 4.6%).
Conclusion
The proportion of esophageal ESD procedures to treat BEA has increased in Japan's Kyushu region. This procedure has a comparable safety profile to similar ESD procedures used to treat other conditions. |
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