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  1. 医学部
  1. 医学部
  2. 学術雑誌掲載論文  (医学部)

Clinical impact of tricuspid regurgitation in patients with acute myocardial infarction

http://hdl.handle.net/10458/0002001795
http://hdl.handle.net/10458/0002001795
4b63893a-4557-43bb-afa8-0b004f0fc579
名前 / ファイル ライセンス アクション
ESC fulltext (3.1 MB)
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アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2025-10-03
タイトル
タイトル Clinical impact of tricuspid regurgitation in patients with acute myocardial infarction
言語 en
言語
言語 eng
キーワード
言語 en
キーワード Echocardiography
キーワード
言語 en
キーワード Myocardial infarction
キーワード
言語 en
キーワード Prognosis
キーワード
言語 en
キーワード Three‐dimensional echocardiography
キーワード
言語 en
キーワード Tricuspid regurgitation
キーワード
言語 en
キーワード Valvular heart disease
資源タイプ
資源タイプ journal article
アクセス権
アクセス権 open access
著者 Nishino, Shun

× Nishino, Shun

en Nishino, Shun(Personal)
Miyazaki Medical Association Hospital Cardiovascular Center

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Nishino, Chiharu

× Nishino, Chiharu

en Nishino, Chiharu(Personal)
Miyazaki Medical Association Hospital Cardiovascular Center

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中井, 陸運

× 中井, 陸運

WEKO 35309
e-Rad_Researcher 50595147

ja 中井, 陸運
宮崎大学

ja-Kana ナカイ, ミチカズ

en Nakai, Michikazu
University of Miyazaki

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Nishihira, Kensaku

× Nishihira, Kensaku

en Nishihira, Kensaku(Personal)
Miyazaki Medical Association Hospital Cardiovascular Center

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Kuriyama, Nehiro

× Kuriyama, Nehiro

en Kuriyama, Nehiro(Personal)
Miyazaki Medical Association Hospital Cardiovascular Center

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Shibata, Yoshisato

× Shibata, Yoshisato

en Shibata, Yoshisato(Personal)
Miyazaki Medical Association Hospital Cardiovascular Center

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内容記述タイプ Abstract
内容記述 The clinical impact of tricuspid regurgitation (TR) in patients after acute myocardial infarction (AMI) is largely unknown. The aim of this study was to clarify the prevalence and prognostic impact of TR in post-AMI patients treated with appropriate primary percutaneous coronary intervention (PCI)./Three hundred fifty-one consecutive patients with first-onset AMI who underwent successful primary PCI from July 2014 to December 2018 were retrospectively examined. Standard two- and three-dimensional echocardiography were performed at discharge. Based on the presence or absence of mild or greater TR, patients were divided into TR (+) and TR (-) groups, respectively. The primary outcome was the incidence of major adverse cardiac events (MACE), defined as the composite of death, re-hospitalization for congestive heart failure and recurrent MI. Seventy-eight (22.2%) patients had mild or greater TR. Kaplan-Meier analysis showed that the cumulative 6-year incidence of MACE was significantly higher in the TR (+) group (hazard ratio, 2.56 [95% confidence interval, 1.48-4.44]; P < 0.001). In the analysis of the severity of TR, the prognosis of patients with mild TR was significantly worse than that of patients without TR (P = 0.026). Multivariable analysis identified the left anterior descending coronary artery as the culprit vessel, left atrial dilation (>34 mL/m2), reduced left ventricular ejection fraction (<50%) and the presence of significant (≥mild) ischaemic mitral regurgitation as independent predictors of mild or greater residual TR after primary PCI for AMI at discharge. Following adjustment for significant clinical parameters, mild or greater TR at discharge was still associated with a significant hazard ratio for the occurrence of MACE (1.87, [95% confidence interval, 1.01-3.48]; P = 0.048)./The presence of mild or greater TR at discharge may serve as a poor prognostic marker in patients with first-onset AMI. In addition to traditional clinical risk factors, it is important to pay more attention to TR and to mana
言語 en
書誌情報 en : ESC heart failure

巻 12, 号 5, p. 3461-3474, 発行日 2025-07-14
出版者
出版者 Wiley
言語 en
ISSN
収録物識別子タイプ EISSN
収録物識別子 20555822
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1002/ehf2.15375
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出版タイプ VoR
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