| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-08-27 |
| タイトル |
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タイトル |
Reevaluating the therapeutic role of extended lymph node dissection in the era of robot-assisted radical prostatectomy |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
open access |
| 著者 |
澤田, 篤郎
WEKO
35206
e-Rad_Researcher
10784796
| ja |
澤田, 篤郎
宮崎大学
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| ja-Kana |
サワダ, アツロウ
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| en |
Sawada, Atsuro
University of Miyazaki
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Search repository
西本, 紘嗣郎
WEKO
35349
e-Rad_Researcher
00365363
| ja |
西本, 紘嗣郎
宮崎大学
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| ja-Kana |
ニシモト, コウシロウ
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| en |
Nishimoto, Koshiro
University of Miyazaki
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Search repository
Akamatsu, Shusuke
Kubota, Masashi
Sumiyoshi, Takayuki
Saito, Ryoichi
Kurahashi, Ryoma
Sekine, Yuya
Negoro, Hiromitsu
Shiraishi, Yusuke
Iguchi, Ryo
Nakashima, Masakazu
Kokura, Kazuki
Iwamura, Hiroshi
Kohei, Naoki
Shimatani, Kimihiro
賀本, 敏行
WEKO
9783
e-Rad_Researcher
00281098
| ja |
賀本, 敏行
宮崎大学
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| ja-Kana |
カモト, トシユキ
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| en |
Kamoto, Toshiyuki
University of Miyazaki
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Search repository
Kobayashi, Takashi
Goto, Takayuki
Daimonji Clinical Application Database (Dai-CAD) study group
| en |
Daimonji Clinical Application Database (Dai-CAD) study group（Organizational）
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Search repository
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
To elucidate the real-world oncological outcomes of robot-assisted radical prostatectomy (RARP) and effectiveness of extended pelvic lymph node dissection (ext-LDN) in the RARP era. Data from 8 194 patients who underwent RARP, including age, clinical T stage, prostate-specific antigen (PSA) before prostate cancer diagnosis (initial PSA), follow-up years, biopsied specimen grade group (GG), and whether they underwent lymph node dissection or not and presurgical androgen deprivation therapy, were recorded. Oncological outcomes among three risk groups (low, intermediate, and poor risks) were analyzed using Kaplan–Meier curves. In intermediate and poor risk cohorts, PSA failure-free, clinical recurrence-free, castration-resistant prostate cancer (CRPC)-free survival, and overall survival (OS) were compared between the ext-LDN groups and no or limited lymph node dissection (no-ltd-LND) groups before and after propensity matching for initial PSA, clinical stage, GG, and androgen deprivation therapy. Four survivals (PSA failure-free, clinical recurrence-free, CRPC-free survival, and OS) were noted among the three risk groups that generally reflected the risks. In comparison between ext-LDN and no-ltd-LND groups, propensity matching matched four factors. No significant difference was observed in the four survivals with or without ext-LDN. In the intermediate-risk, high-risk, and locally advanced cohorts (cT3–4), similar analyses were performed as the subanalyses |
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言語 |
en |
| 書誌情報 |
en : Scientific Reports
巻 15,
p. 17680,
発行日 2025-05-21
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| 出版者 |
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出版者 |
Springer Nature |
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言語 |
en |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
20452322 |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1038/s41598-025-00926-2 |
| 著者版フラグ |
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出版タイプ |
VoR |
Fulltext (6.7 MB)
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