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  1. 医学部
  1. 医学部
  2. 学術雑誌掲載論文  (医学部)

Influence of Posterior Decompression for Lumbar Spinal Canal Stenosis on Intervertebral Disc Degeneration on Magnetic Resonance Imaging

http://hdl.handle.net/10458/0002001618
http://hdl.handle.net/10458/0002001618
4cf5cbbf-fac4-44bb-9e70-a767248bdd24
名前 / ファイル ライセンス アクション
20250627-351911-bmf1pq.pdf fulltext (1.3 MB)
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アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2025-08-19
タイトル
タイトル Influence of Posterior Decompression for Lumbar Spinal Canal Stenosis on Intervertebral Disc Degeneration on Magnetic Resonance Imaging
言語 en
言語
言語 eng
資源タイプ
資源タイプ journal article
アクセス権
アクセス権 open access
著者 亀井, 直輔

× 亀井, 直輔

WEKO 35566
e-Rad_Researcher 70444685

ja 亀井, 直輔
宮崎大学

ja-Kana カメイ, ナオスケ

en Kamei, Naosuke
University of Miyazaki

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Nakamae, Toshio

× Nakamae, Toshio

en Nakamae, Toshio
Hiroshima University

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Adachi, Nobuo

× Adachi, Nobuo

en Adachi, Nobuo
Hiroshima University

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抄録
内容記述タイプ Abstract
内容記述 Introduction
Posterior decompression surgery for lumbar spinal canal stenosis (LSCS) is minimally invasive but may cause intervertebral instability and disc degeneration due to the removal of posterior support structures. This study aimed to evaluate the impact of decompression surgery on intervertebral disc degeneration using magnetic resonance imaging (MRI)-based signal ratio (SR) and disc ratio (DR) parameters.

Methods
Patients who underwent MRI three months to two years after decompression surgery for LSCS were included. Exclusion criteria included decompression at three or more levels, infections, and epidural hematomas. Sixty-three intervertebral discs from 51 patients were analyzed. SR was calculated as the ratio of the T2 signal intensity of the disc to that of the spinal cord, while DR compared the decompressed disc to the T12-L1 disc. Pre and postoperative SR and DR values were compared, and their associations with revision surgery were analyzed using multiple regression.

Results
Postoperative SR (0.402±0.225) and DR (0.642±0.299) were significantly lower than preoperative values (SR: 0.461±0.223, DR: 0.695±0.276; both p<0.05), indicating disc degeneration. Revision surgery occurred in 16 patients (31%), predominantly younger males. However, no significant association was found between MRI parameters and revision surgery. Regression analysis identified age (odds ratio: 0.889, p=0.014) and sex (female, odds ratio: 0.071, p=0.005) as independent factors for revision surgery. The revision surgery group had a younger mean age (67.2 ± 10.6 years) as compared to the control group (74.5 ± 7.4 years). Additionally, the proportion of males was higher in the revision surgery group (81.3%) than in the control group (45.7%).

Conclusions
Decompression surgery for LSCS resulted in short-term disc degeneration. Despite this progression, disc degeneration was not associated with the need for revision surgery. These findings suggest that early postoperative disc degeneration does not adversely affect the clinical course and therefore should not be regarded as a reason to avoid decompression surgery.
言語 en
書誌情報 en : Cureus

巻 17, 号 5, p. e84992, 発行日 2025-05-28
出版者
出版者 Springer Science and Business Media LLC
言語 en
ISSN
収録物識別子タイプ PISSN
収録物識別子 2168-8184
DOI
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識別子タイプ DOI
関連識別子 https://doi.org/10.7759/cureus.84992
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出版タイプ VoR
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