| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-07-21 |
| タイトル |
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タイトル |
Histopathology of nasopharyngeal and palatine tonsils in Japanese black calves naturally infected with Mycoplasma bovis |
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言語 |
en |
| 言語 |
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言語 |
eng |
| キーワード |
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言語 |
en |
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キーワード |
bovine respiratory disease complex |
| キーワード |
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言語 |
en |
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キーワード |
cattle |
| キーワード |
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言語 |
en |
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キーワード |
Mycoplasma bovis |
| キーワード |
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言語 |
en |
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キーワード |
nasopharyngeal tonsil |
| キーワード |
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言語 |
en |
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キーワード |
palatine tonsil |
| 資源タイプ |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
open access |
| 著者 |
Ahmed, Amaal Ezzat
Nakai, Mutsumi
Kakiya, Miho
福家, 直幸
WEKO
34661
e-Rad_Researcher
70984558
| ja |
福家, 直幸
宮崎大学
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| ja-Kana |
フケ, ナオユキ
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| en |
Fuke, Naoyuki
University of Miyazaki
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Search repository
Hegazy, Asmaa A
Kondo, Hiroaki
平井, 卓哉
WEKO
25970
e-Rad_Researcher
60321668
| ja |
平井, 卓哉
宮崎大学
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| ja-Kana |
ヒライ, タクヤ
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| en |
Hirai, Takuya
University of Miyazaki
|
Search repository
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Mycoplasma bovis (M. bovis) is an important bacterium in the bovine respiratory disease complex (BRDC), which causes significant economic losses. The nasopharyngeal and palatine tonsils are mucosal-associated lymphoid tissue components that are the initial barrier to respiratory pathogens. In the present study, we investigated 5 pneumonic Japanese black and 3 control calves (2 Japanese black and 1 Holstein). The localization of M. bovis in the nasopharyngeal, palatine tonsils, and lungs was examined using nested and multiplex polymerase chain reaction (PCR), histopathology, and in situ hybridization (ISH) techniques. Nested PCR revealed that all examined tissues from all pneumonic calves were positive for M. bovis infection, but not the control. Histopathology revealed suppurative nasopharyngeal tonsillitis and palatine tonsillar cryptitis in all cases. Surprisingly, prominent histologic changes were observed in the palatine tonsils but not in the nasopharyngeal tonsils. Necrotizing suppurative bronchopneumonia was observed in 4 pneumonic calves. In ISH analysis, positive hybridization signals adherent to and/or within the surface epithelium of nasopharyngeal tonsils and crypt epithelium of nasopharyngeal and palatine tonsils were observed. Additionally, these signals were seen in the palatine tonsillar cryptic detritus. In the lungs, ISH signals were observed in necrotic areas, the bronchial epithelium, and pulmonary inflammatory exudate. These findings suggest that the nasopharyngeal and palatine tonsils are the primary sites of M. bovis infection. Also, M. bovis can colonize the detritus in the crypts of the palatine tonsils of the pneumonic animals. |
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言語 |
en |
| 書誌情報 |
en : The Journal of Veterinary Medical Science
巻 87,
号 8,
p. 924-933,
発行日 2025
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| 出版者 |
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出版者 |
Japanese Society of Veterinary Science |
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言語 |
en |
| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0916-7250 |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
1347-7439 |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1292/jvms.25-0188 |
| 権利 |
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権利情報 |
© 2025 by the Japanese Society of Veterinary Science |
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言語 |
en |
| 著者版フラグ |
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出版タイプ |
VoR |
fulltext (7.5 MB)
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