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  1. 医学部
  1. 医学部
  2. 学術雑誌掲載論文  (医学部)

Trends in the causes of stillbirths over 20 years in Southern Japan

http://hdl.handle.net/10458/0002001509
http://hdl.handle.net/10458/0002001509
1412aa9e-c4b9-48e6-9aa1-8becb6e26359
名前 / ファイル ライセンス アクション
s12884-025-07794-8.pdf Fulltext (1.4 MB)
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アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2025-07-21
タイトル
タイトル Trends in the causes of stillbirths over 20 years in Southern Japan
言語 en
言語
言語 eng
キーワード
言語 en
キーワード Asphyxia
キーワード
言語 en
キーワード Chorioamnionitis
キーワード
言語 en
キーワード Congenital defects
キーワード
言語 en
キーワード Fetal growth restriction
キーワード
言語 en
キーワード Placental abruption
キーワード
言語 en
キーワード Stillbirth
キーワード
言語 en
キーワード Umbilical cord
資源タイプ
資源タイプ journal article
アクセス権
アクセス権 open access
著者 Kino, Emi

× Kino, Emi

en Kino, Emi
University of Miyazaki

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Maki, Yohei

× Maki, Yohei

en Maki, Yohei
Miyazaki Medical Association Hospital

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山田, 直史

× 山田, 直史

WEKO 27908

en Yamada, Naoshi

ja 山田, 直史

ja-Kana ヤマダ, ナオシ

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児玉, 由紀

× 児玉, 由紀

WEKO 24698
e-Rad_Researcher 30305081

ja 児玉, 由紀
宮崎大学

ja-Kana コダマ, ユキ

en Kodama, Yuki
University of Miyazaki

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桂木, 真司

× 桂木, 真司

WEKO 34852
e-Rad_Researcher 50521283

ja 桂木, 真司
宮崎大学

ja-Kana カツラギ, シンジ

en Katsuragi, Shinji
University of Miyazaki

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鮫島, 浩

× 鮫島, 浩

WEKO 7804
e-Rad_Researcher 50274775

ja 鮫島, 浩
宮崎大学

ja-Kana サメシマ, ヒロシ

en Sameshima, Hiroshi
University of Miyazaki

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池ノ上, 克

× 池ノ上, 克

WEKO 7806

en Ikenoue, Tsuyomu

ja 池ノ上, 克

ja-Kana イケノウエ, ツヨム

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抄録
内容記述タイプ Abstract
内容記述 Background
This study aimed to determine the temporal trend in the causes of stillbirths over a period of two decades using a regional perinatal database in order to facilitate the development of perinatal strategies to prevent stillbirths in Japan.

Methods
This was a population-based retrospective study. Cases of perinatal death and neurological damage were reported by perinatal centers and primary birth clinics, followed by their peer review and audit, and final registration in the database. Data for stillbirths, defined as fetal death at ≥ 22 weeks of gestation between January 1, 2001, and December 31, 2020, were extracted from the database. Causes of stillbirths were reclassified according to the ReCoDe system. Temporal trends in the causes of stillbirths per 1,000 births and proportion of the causes were evaluated using the Cochran-Armitage test.

Results
Over the 20 years, in the study region, a total of 205,025 were delivered at ≥ 22 weeks of gestation, and 569 were stillborn (2.8 per 1,000 births). The most common cause of stillbirth was “no relevant condition identified” in 39.5% cases, followed by “abruption” in 12.3%, “lethal congenital anomaly” in 9.5%, and “umbilical cord, other” in 5.8%. The trends in stillbirths caused by “fetal growth restriction,” “abruption,” “asphyxia,” and “no relevant condition identified” significantly decreased. However, no change in trend due to “lethal congenital anomaly” was seen. The stillbirth trend caused by “cord, other” significantly increased. The proportion of stillbirths related to unidentified causes remained unchanged.

Conclusions
Over the 20-year period, the rate of stillbirths caused by abruption, fetal growth restriction, and asphyxia, which can be reduced by early detection and intervention, decreased. The incidence of stillbirths caused by cord constriction increased. Investigations to prevent cord-accident stillbirths would be required to further reduce stillbirths in the study region. Establishment of algorithms that allow the identification of the causes of stillbirths would be crucial to reduce instances of stillbirths due to unidentified causes.
言語 en
書誌情報 en : BMC Pregnancy and Childbirth

巻 25, p. 654, 発行日 2025-06-04
出版者
出版者 Springer Science and Business Media LLC
言語 en
ISSN
収録物識別子タイプ EISSN
収録物識別子 14712393
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1186/s12884-025-07794-8
著者版フラグ
出版タイプ VoR
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